Amantadine penetration into cerebrospinal fluid of a child with influenza A encephalitis

Joseph M. Geskey, Neal J. Thomas

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

The use of amantadine has been advocated as treatment for influenza A encephalitis despite limited information regarding cerebrospinal fluid concentrations and the pathogenesis of encephalitis associated with influenza virus infections. We report a 2-year-old child with influenza A encephalitis treated with amantadine who achieved a potentially therapeutic concentration in cerebrospinal fluid. Despite this the child developed significant neurologic impairment.

Original languageEnglish (US)
Pages (from-to)270-272
Number of pages3
JournalPediatric Infectious Disease Journal
Volume23
Issue number3
DOIs
StatePublished - Mar 1 2004

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)
  • Infectious Diseases

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