Aminoglutethimide medical adrenalectomy for advanced prostatic carcinoma

E. J. Sanford, J. R. Drago, T. J. Rohner, R. Santen, Allan Lipton

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

Complete adrenal suppression with aminoglutethimide has been accomplished in 7 patients with progressive stage D carcinoma of the prostate who had become refractory to orchiectomy and the administration of exogenous estrogens. A favorable response was noted in 3 patients. These preliminary results indicate that this agent may be as useful as surgical adrenalectomy in the treatment of progressive prostatic carcinoma. A brief discussion of the pharmacology of this agent, its mode of administration and the side effects are presented.

Original languageEnglish (US)
Pages (from-to)170-174
Number of pages5
JournalUnknown Journal
Volume115
Issue number2
DOIs
StatePublished - Jan 1 1976

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Aminoglutethimide
Adrenalectomy
Carcinoma
Orchiectomy
Prostate
Estrogens
Pharmacology
Therapeutics

All Science Journal Classification (ASJC) codes

  • Urology

Cite this

Sanford, E. J. ; Drago, J. R. ; Rohner, T. J. ; Santen, R. ; Lipton, Allan. / Aminoglutethimide medical adrenalectomy for advanced prostatic carcinoma. In: Unknown Journal. 1976 ; Vol. 115, No. 2. pp. 170-174.
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Aminoglutethimide medical adrenalectomy for advanced prostatic carcinoma. / Sanford, E. J.; Drago, J. R.; Rohner, T. J.; Santen, R.; Lipton, Allan.

In: Unknown Journal, Vol. 115, No. 2, 01.01.1976, p. 170-174.

Research output: Contribution to journalArticle

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