Aminoglutethimide medical adrenalectomy for advanced prostatic carcinoma

E. J. Sanford, J. R. Drago, T. J. Rohner, R. Santen, Allan Lipton

Research output: Contribution to journalArticlepeer-review

44 Scopus citations


Complete adrenal suppression with aminoglutethimide has been accomplished in 7 patients with progressive stage D carcinoma of the prostate who had become refractory to orchiectomy and the administration of exogenous estrogens. A favorable response was noted in 3 patients. These preliminary results indicate that this agent may be as useful as surgical adrenalectomy in the treatment of progressive prostatic carcinoma. A brief discussion of the pharmacology of this agent, its mode of administration and the side effects are presented.

Original languageEnglish (US)
Pages (from-to)170-174
Number of pages5
JournalUnknown Journal
Issue number2
StatePublished - Jan 1 1976

All Science Journal Classification (ASJC) codes

  • Urology


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