A method is described for measuring human alpha-fetoprotein concentration (AFP) in amniotic fluid by laser immunonephelometry showing results comparable with those obtained by radioimmunoassay. Advantages gained with the laser technique lie in its simplicity as a method which avoids use of radioactive materials, a more rapid 2 h turnaround time and a relatively small capital equipment outlay with minimal operating costs. Laser immunonephelometry appears to be an excellent alternative to radioimmunoassay for measuring AFP in amniotic fluid.
All Science Journal Classification (ASJC) codes
- Clinical Biochemistry
- Biochemistry, medical