An adaptive evolutionary shift in Fusarium head blight pathogen populations is driving the rapid spread of more toxigenic Fusarium graminearum in North America

Todd J. Ward, Randall M. Clear, Alejandro P. Rooney, Kerry O'Donnell, Don Gaba, Susan Patrick, David E. Starkey, Jeannie Gilbert, David Michael Geiser, Tom W. Nowicki

Research output: Contribution to journalArticle

297 Citations (Scopus)

Abstract

Analysis of Fusarium head blight (FHB) pathogen diversity revealed that 3ADON producing Fusarium graminearum are prevalent in North America and identified significant population structure associated with trichothecene chemotype differences (FST > 0.285; P < 0.001). In addition, we identified a trichothecene chemotype cline in Canada and documented a recent and significant shift in FHB pathogen composition by demonstrating that the 3ADON chemotype frequency in western Canada increased more than 14-fold between 1998 and 2004. On average, isolates from 3ADON populations produced significantly (P < 0.05) more trichothecene and had significantly (P < 0.005) higher fecundity and growth rates than isolates from the 15ADON population. These results indicate that selection is driving the rapid spread of an introduced pathogen population that is more toxigenic and potentially more vigorous. The discovery of this previously unrecognized pathogen diversity has significant implications for food safety and cereal production in North America.

Original languageEnglish (US)
Pages (from-to)473-484
Number of pages12
JournalFungal Genetics and Biology
Volume45
Issue number4
DOIs
StatePublished - Apr 1 2008

Fingerprint

Fusarium
Trichothecenes
North America
Population
Canada
Food Safety
Fertility
Growth

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Genetics

Cite this

Ward, Todd J. ; Clear, Randall M. ; Rooney, Alejandro P. ; O'Donnell, Kerry ; Gaba, Don ; Patrick, Susan ; Starkey, David E. ; Gilbert, Jeannie ; Geiser, David Michael ; Nowicki, Tom W. / An adaptive evolutionary shift in Fusarium head blight pathogen populations is driving the rapid spread of more toxigenic Fusarium graminearum in North America. In: Fungal Genetics and Biology. 2008 ; Vol. 45, No. 4. pp. 473-484.
@article{6911a33210304df0905ffc8078776439,
title = "An adaptive evolutionary shift in Fusarium head blight pathogen populations is driving the rapid spread of more toxigenic Fusarium graminearum in North America",
abstract = "Analysis of Fusarium head blight (FHB) pathogen diversity revealed that 3ADON producing Fusarium graminearum are prevalent in North America and identified significant population structure associated with trichothecene chemotype differences (FST > 0.285; P < 0.001). In addition, we identified a trichothecene chemotype cline in Canada and documented a recent and significant shift in FHB pathogen composition by demonstrating that the 3ADON chemotype frequency in western Canada increased more than 14-fold between 1998 and 2004. On average, isolates from 3ADON populations produced significantly (P < 0.05) more trichothecene and had significantly (P < 0.005) higher fecundity and growth rates than isolates from the 15ADON population. These results indicate that selection is driving the rapid spread of an introduced pathogen population that is more toxigenic and potentially more vigorous. The discovery of this previously unrecognized pathogen diversity has significant implications for food safety and cereal production in North America.",
author = "Ward, {Todd J.} and Clear, {Randall M.} and Rooney, {Alejandro P.} and Kerry O'Donnell and Don Gaba and Susan Patrick and Starkey, {David E.} and Jeannie Gilbert and Geiser, {David Michael} and Nowicki, {Tom W.}",
year = "2008",
month = "4",
day = "1",
doi = "10.1016/j.fgb.2007.10.003",
language = "English (US)",
volume = "45",
pages = "473--484",
journal = "Fungal Genetics and Biology",
issn = "1087-1845",
publisher = "Academic Press Inc.",
number = "4",

}

An adaptive evolutionary shift in Fusarium head blight pathogen populations is driving the rapid spread of more toxigenic Fusarium graminearum in North America. / Ward, Todd J.; Clear, Randall M.; Rooney, Alejandro P.; O'Donnell, Kerry; Gaba, Don; Patrick, Susan; Starkey, David E.; Gilbert, Jeannie; Geiser, David Michael; Nowicki, Tom W.

In: Fungal Genetics and Biology, Vol. 45, No. 4, 01.04.2008, p. 473-484.

Research output: Contribution to journalArticle

TY - JOUR

T1 - An adaptive evolutionary shift in Fusarium head blight pathogen populations is driving the rapid spread of more toxigenic Fusarium graminearum in North America

AU - Ward, Todd J.

AU - Clear, Randall M.

AU - Rooney, Alejandro P.

AU - O'Donnell, Kerry

AU - Gaba, Don

AU - Patrick, Susan

AU - Starkey, David E.

AU - Gilbert, Jeannie

AU - Geiser, David Michael

AU - Nowicki, Tom W.

PY - 2008/4/1

Y1 - 2008/4/1

N2 - Analysis of Fusarium head blight (FHB) pathogen diversity revealed that 3ADON producing Fusarium graminearum are prevalent in North America and identified significant population structure associated with trichothecene chemotype differences (FST > 0.285; P < 0.001). In addition, we identified a trichothecene chemotype cline in Canada and documented a recent and significant shift in FHB pathogen composition by demonstrating that the 3ADON chemotype frequency in western Canada increased more than 14-fold between 1998 and 2004. On average, isolates from 3ADON populations produced significantly (P < 0.05) more trichothecene and had significantly (P < 0.005) higher fecundity and growth rates than isolates from the 15ADON population. These results indicate that selection is driving the rapid spread of an introduced pathogen population that is more toxigenic and potentially more vigorous. The discovery of this previously unrecognized pathogen diversity has significant implications for food safety and cereal production in North America.

AB - Analysis of Fusarium head blight (FHB) pathogen diversity revealed that 3ADON producing Fusarium graminearum are prevalent in North America and identified significant population structure associated with trichothecene chemotype differences (FST > 0.285; P < 0.001). In addition, we identified a trichothecene chemotype cline in Canada and documented a recent and significant shift in FHB pathogen composition by demonstrating that the 3ADON chemotype frequency in western Canada increased more than 14-fold between 1998 and 2004. On average, isolates from 3ADON populations produced significantly (P < 0.05) more trichothecene and had significantly (P < 0.005) higher fecundity and growth rates than isolates from the 15ADON population. These results indicate that selection is driving the rapid spread of an introduced pathogen population that is more toxigenic and potentially more vigorous. The discovery of this previously unrecognized pathogen diversity has significant implications for food safety and cereal production in North America.

UR - http://www.scopus.com/inward/record.url?scp=39749180997&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=39749180997&partnerID=8YFLogxK

U2 - 10.1016/j.fgb.2007.10.003

DO - 10.1016/j.fgb.2007.10.003

M3 - Article

C2 - 18035565

AN - SCOPUS:39749180997

VL - 45

SP - 473

EP - 484

JO - Fungal Genetics and Biology

JF - Fungal Genetics and Biology

SN - 1087-1845

IS - 4

ER -