An Advanced Physiological Controller Design for a Left Ventricular Assist Device to Prevent Left Ventricular Collapse

Yi Wu, Paul Allaire, Gang Tao, Houston Wood, Don Olsen, Curt Tribble

Research output: Contribution to journalArticle

48 Scopus citations


A continuous flow left ventricle assist device (LVAD), which is mainly composed of a continuous flow blood pump and a physiological controller, has only one control input, the rotational speed of the pump, but at least three performance criteria to meet. The challenge for the physiological controller of a long-term continuous flow LVAD is the adaptability to different cardiovascular loading situations and the ability to handle systemic and parametric uncertainties with only one control input. The physiological LVAD controller presented in this article exhibits good performance in terms of the three performance criteria in different physiological loading conditions, such as disturbance, resting, and moderate exercise, for a patient with congestive heart failure. The collapse of the left ventricle, which is an inherent problem for a continuous flow LVAD, has been prevented because of the control algorithm design.

Original languageEnglish (US)
Pages (from-to)926-930
Number of pages5
JournalArtificial organs
Issue number10
StatePublished - Oct 1 2003


All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomaterials
  • Biomedical Engineering

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