An approach to the aryl-C-glycoside DEF-ring system of nogalamycin

Richard P. Joyce, M. Parvez, Steven M. Weinreb

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

Ketone 16, a key intermediate in synthesis of the nogalamycin DEF-rings, has been efficiently and stereospecifically synthesized in nine steps using a strategy centered on an intramolecular N-sulfinyl dienophile Diels-Alder cycloaddition.

Original languageEnglish (US)
Pages (from-to)4885-4888
Number of pages4
JournalTetrahedron Letters
Volume27
Issue number40
DOIs
StatePublished - 1986

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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