An approach to total synthesis of the cylindricine B pyridoquinoline subclass of tricyclic marine ascidian alkaloids

Wenchun Chao, Yogesh R. Mahajan, Steven M. Weinreb

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

Employing an intramolecular N-acylketiminium ion/olefin hetero Diels-Alder reaction, and a ring closing metathesis of a vinyl chloride as pivotal steps, it is possible to directly access the pyridoquinoline tricyclic ring system of the marine alkaloids cylindrines B and J.

Original languageEnglish (US)
Pages (from-to)3815-3818
Number of pages4
JournalTetrahedron Letters
Volume47
Issue number23
DOIs
StatePublished - Jun 5 2006

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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