An estimated compliance index derived from intracranial pressure recording

Michael L. Daley, M. Pourcyous, G. Stidham, Shelly Timmons, C. W. Leffler

Research output: Contribution to journalArticle

Abstract

The purpose of this study is to test the validity of a proposed compliance index, percent change of compliance per mmHg of intracranial pressure (%CC/mmHg), by comparison of values of the index with corresponding experimentally derived values of compliance. The derivation of %CC/mmHg is based on two assumptions: I) the pressure-volume characteristic of the craniospinal sac can be linearized for small perturbations about an equilibrium; and 2) during a brief interval in which these perturbations occur the pathophysiologic state of the sac does not significantly change. By rapid infusion of 0.2 ml of mock cerebrospinal fluid (CSF) experimental values of compliance (n = 44) were obtained from 10 piglets during monitoring of intracranial pressure (ICP). A strong correlation (r = 0.89, p < .001, n = 44) was obtained between values of %CC/mmHg and corresponding values of experimentally derived compliance (ml/mmHg). The value of the proposed index of compliance, %CC/mmHg, needs to be evaluated in the clinical setting. However, from the view of validation of ICP instrumentation, high values of both mean ICP and mean %CC/mmHg are contradictory and indicative of the occurrence of instrumentation error due to electronic direct current drift.

Original languageEnglish (US)
Pages (from-to)183-185
Number of pages3
JournalActa Neurochirurgica, Supplement
Issue number81
DOIs
StatePublished - Jan 1 2002

Fingerprint

Intracranial Pressure
Compliance
Cerebrospinal Fluid
Pressure

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology

Cite this

Daley, Michael L. ; Pourcyous, M. ; Stidham, G. ; Timmons, Shelly ; Leffler, C. W. / An estimated compliance index derived from intracranial pressure recording. In: Acta Neurochirurgica, Supplement. 2002 ; No. 81. pp. 183-185.
@article{3d8856ef8d3644dc8844bb84a562de4b,
title = "An estimated compliance index derived from intracranial pressure recording",
abstract = "The purpose of this study is to test the validity of a proposed compliance index, percent change of compliance per mmHg of intracranial pressure ({\%}CC/mmHg), by comparison of values of the index with corresponding experimentally derived values of compliance. The derivation of {\%}CC/mmHg is based on two assumptions: I) the pressure-volume characteristic of the craniospinal sac can be linearized for small perturbations about an equilibrium; and 2) during a brief interval in which these perturbations occur the pathophysiologic state of the sac does not significantly change. By rapid infusion of 0.2 ml of mock cerebrospinal fluid (CSF) experimental values of compliance (n = 44) were obtained from 10 piglets during monitoring of intracranial pressure (ICP). A strong correlation (r = 0.89, p < .001, n = 44) was obtained between values of {\%}CC/mmHg and corresponding values of experimentally derived compliance (ml/mmHg). The value of the proposed index of compliance, {\%}CC/mmHg, needs to be evaluated in the clinical setting. However, from the view of validation of ICP instrumentation, high values of both mean ICP and mean {\%}CC/mmHg are contradictory and indicative of the occurrence of instrumentation error due to electronic direct current drift.",
author = "Daley, {Michael L.} and M. Pourcyous and G. Stidham and Shelly Timmons and Leffler, {C. W.}",
year = "2002",
month = "1",
day = "1",
doi = "10.1007/978-3-7091-6738-0_48",
language = "English (US)",
pages = "183--185",
journal = "Acta Neurochirurgica, Supplement",
issn = "0065-1419",
publisher = "Springer Wien",
number = "81",

}

An estimated compliance index derived from intracranial pressure recording. / Daley, Michael L.; Pourcyous, M.; Stidham, G.; Timmons, Shelly; Leffler, C. W.

In: Acta Neurochirurgica, Supplement, No. 81, 01.01.2002, p. 183-185.

Research output: Contribution to journalArticle

TY - JOUR

T1 - An estimated compliance index derived from intracranial pressure recording

AU - Daley, Michael L.

AU - Pourcyous, M.

AU - Stidham, G.

AU - Timmons, Shelly

AU - Leffler, C. W.

PY - 2002/1/1

Y1 - 2002/1/1

N2 - The purpose of this study is to test the validity of a proposed compliance index, percent change of compliance per mmHg of intracranial pressure (%CC/mmHg), by comparison of values of the index with corresponding experimentally derived values of compliance. The derivation of %CC/mmHg is based on two assumptions: I) the pressure-volume characteristic of the craniospinal sac can be linearized for small perturbations about an equilibrium; and 2) during a brief interval in which these perturbations occur the pathophysiologic state of the sac does not significantly change. By rapid infusion of 0.2 ml of mock cerebrospinal fluid (CSF) experimental values of compliance (n = 44) were obtained from 10 piglets during monitoring of intracranial pressure (ICP). A strong correlation (r = 0.89, p < .001, n = 44) was obtained between values of %CC/mmHg and corresponding values of experimentally derived compliance (ml/mmHg). The value of the proposed index of compliance, %CC/mmHg, needs to be evaluated in the clinical setting. However, from the view of validation of ICP instrumentation, high values of both mean ICP and mean %CC/mmHg are contradictory and indicative of the occurrence of instrumentation error due to electronic direct current drift.

AB - The purpose of this study is to test the validity of a proposed compliance index, percent change of compliance per mmHg of intracranial pressure (%CC/mmHg), by comparison of values of the index with corresponding experimentally derived values of compliance. The derivation of %CC/mmHg is based on two assumptions: I) the pressure-volume characteristic of the craniospinal sac can be linearized for small perturbations about an equilibrium; and 2) during a brief interval in which these perturbations occur the pathophysiologic state of the sac does not significantly change. By rapid infusion of 0.2 ml of mock cerebrospinal fluid (CSF) experimental values of compliance (n = 44) were obtained from 10 piglets during monitoring of intracranial pressure (ICP). A strong correlation (r = 0.89, p < .001, n = 44) was obtained between values of %CC/mmHg and corresponding values of experimentally derived compliance (ml/mmHg). The value of the proposed index of compliance, %CC/mmHg, needs to be evaluated in the clinical setting. However, from the view of validation of ICP instrumentation, high values of both mean ICP and mean %CC/mmHg are contradictory and indicative of the occurrence of instrumentation error due to electronic direct current drift.

UR - http://www.scopus.com/inward/record.url?scp=0035989192&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035989192&partnerID=8YFLogxK

U2 - 10.1007/978-3-7091-6738-0_48

DO - 10.1007/978-3-7091-6738-0_48

M3 - Article

C2 - 12168299

AN - SCOPUS:0035989192

SP - 183

EP - 185

JO - Acta Neurochirurgica, Supplement

JF - Acta Neurochirurgica, Supplement

SN - 0065-1419

IS - 81

ER -