An exploratory study of depot-medroxyprogesterone acetate and bone mineral density in adolescent and young adult women with cerebral palsy

R. Claire Roden, Garey Noritz, Erin R. McKnight, Andrea E. Bonny

Research output: Contribution to journalArticle

Abstract

Objective: To explore whether use of depot-medroxyprogesterone acetate (DMPA) in adolescent and young adult females with cerebral palsy is associated with lower bone mineral density (BMD). Methods: A chart review of adolescent and young adult females with cerebral palsy who had undergone dual-energy X-ray absorptiometry, comparing BMD among those with (n = 19) and without DMPA (n = 84) exposure. Results: BMD was similar in patients with and without DMPA exposure. All patients had low BMD, with average Z-scores of less than −2 at most sites. Conclusion: Results suggest that DMPA is not associated with lower BMD in non-ambulatory adolescent and young adult females with cerebral palsy.

Original languageEnglish (US)
JournalContraception
DOIs
Publication statusAccepted/In press - Jan 1 2020

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All Science Journal Classification (ASJC) codes

  • Reproductive Medicine
  • Obstetrics and Gynecology

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