An integrated approach to diabetic retinopathy research

Thomas W. Gardner, Steven F. Abcouwer, Alistair J. Barber, Gregory R. Jackson

Research output: Contribution to journalReview article

45 Citations (Scopus)

Abstract

This review discusses the pathophysiology of diabetic retinopathy related to direct effects of loss of insulin receptor action and metabolic dysregulation on the retina. The resulting sensory neuropathy can be diagnosed by structural and functional tests in patients with mild nonproliferative diabetic retinopathy. Research teams can collaborate to integrate ocular and systemic factors that impair vision and to design strategies to maintain retinal function in persons with diabetes mellitus. Evolving concepts may lead to inclusion of tests of retinal function in the detection of diabetic retinopathy and neuroprotective strategies to preserve vision for persons with diabetes.

Original languageEnglish (US)
Pages (from-to)230-235
Number of pages6
JournalArchives of Ophthalmology
Volume129
Issue number2
DOIs
StatePublished - Feb 1 2011

Fingerprint

Diabetic Retinopathy
Research
Insulin Receptor
Retina
Diabetes Mellitus

All Science Journal Classification (ASJC) codes

  • Ophthalmology

Cite this

Gardner, Thomas W. ; Abcouwer, Steven F. ; Barber, Alistair J. ; Jackson, Gregory R. / An integrated approach to diabetic retinopathy research. In: Archives of Ophthalmology. 2011 ; Vol. 129, No. 2. pp. 230-235.
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An integrated approach to diabetic retinopathy research. / Gardner, Thomas W.; Abcouwer, Steven F.; Barber, Alistair J.; Jackson, Gregory R.

In: Archives of Ophthalmology, Vol. 129, No. 2, 01.02.2011, p. 230-235.

Research output: Contribution to journalReview article

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