An interactive computer program can effectively educate patients about genetic testing for breast cancer susceptibility

Michael Green, Barbara B. Biesecker, Aideen M. McInerney, David Mauger, Norman Fost

Research output: Contribution to journalArticle

100 Citations (Scopus)

Abstract

As genetic testing for susceptibility to breast cancer becomes more widespread, alternative methods for educating individuals prior to testing will be needed. Our objective was to compare face-to-face education and counseling by a genetic counselor with education by an interactive computer program, assessing the effects of each on knowledge of breast cancer genetics and intent to undergo genetic testing. We used a randomized, controlled trial. Seventy-two self-referred women with a first-degree relative with breast cancer received outpatient education and counseling at the Clinical Center of the National Institutes of Health (NIH). Twenty-nine received individualized counseling from a genetic counselor (counseling group), 29 received education from an interactive computer program followed by individualized counseling (computer group), and 14 were controls. Both pre- and postintervention assessment of knowledge about breast cancer genetics and intent to undergo genetic testing were measured. The control group participants correctly answered 74% of the knowledge questions; the counselor group, 92%; and the computer group, 96% (P < .0001). Unadjusted mean knowledge scores were significantly higher in the computer group than the counselor group (P = .048), but they were equivalent when adjusted for demographic differences (P = 0.34). Intent to undergo genetic testing was influenced by the interventions: preintervention, a majority in all groups (69%) indicated that they were likely (definitely and most likely) to undergo testing; after either intervention coupled with counseling, only 44% indicated that they were likely to do so (P = .0002; odds ratio = 2.8, 95% CI = 1.7-4.9). We concluded that a computer program can successfully educate patients about breast cancer susceptibility, and, along with genetic counseling, can influence patients' intentions to undergo genetic testing.

Original languageEnglish (US)
Pages (from-to)16-23
Number of pages8
JournalAmerican Journal of Medical Genetics
Volume103
Issue number1
DOIs
StatePublished - Sep 15 2001

Fingerprint

Genetic Testing
Software
Counseling
Breast Neoplasms
Genetic Counseling
Education
National Institutes of Health (U.S.)
Genetic Predisposition to Disease
Outpatients
Randomized Controlled Trials
Odds Ratio
Demography
Control Groups
Counselors

All Science Journal Classification (ASJC) codes

  • Genetics
  • Genetics(clinical)

Cite this

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abstract = "As genetic testing for susceptibility to breast cancer becomes more widespread, alternative methods for educating individuals prior to testing will be needed. Our objective was to compare face-to-face education and counseling by a genetic counselor with education by an interactive computer program, assessing the effects of each on knowledge of breast cancer genetics and intent to undergo genetic testing. We used a randomized, controlled trial. Seventy-two self-referred women with a first-degree relative with breast cancer received outpatient education and counseling at the Clinical Center of the National Institutes of Health (NIH). Twenty-nine received individualized counseling from a genetic counselor (counseling group), 29 received education from an interactive computer program followed by individualized counseling (computer group), and 14 were controls. Both pre- and postintervention assessment of knowledge about breast cancer genetics and intent to undergo genetic testing were measured. The control group participants correctly answered 74{\%} of the knowledge questions; the counselor group, 92{\%}; and the computer group, 96{\%} (P < .0001). Unadjusted mean knowledge scores were significantly higher in the computer group than the counselor group (P = .048), but they were equivalent when adjusted for demographic differences (P = 0.34). Intent to undergo genetic testing was influenced by the interventions: preintervention, a majority in all groups (69{\%}) indicated that they were likely (definitely and most likely) to undergo testing; after either intervention coupled with counseling, only 44{\%} indicated that they were likely to do so (P = .0002; odds ratio = 2.8, 95{\%} CI = 1.7-4.9). We concluded that a computer program can successfully educate patients about breast cancer susceptibility, and, along with genetic counseling, can influence patients' intentions to undergo genetic testing.",
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An interactive computer program can effectively educate patients about genetic testing for breast cancer susceptibility. / Green, Michael; Biesecker, Barbara B.; McInerney, Aideen M.; Mauger, David; Fost, Norman.

In: American Journal of Medical Genetics, Vol. 103, No. 1, 15.09.2001, p. 16-23.

Research output: Contribution to journalArticle

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