An Investigation of the Intramolecular Ene Reaction of N-Acyl Imines

Jyh Ming Lin, Kevin Koch, Frank W. Fowler

Research output: Contribution to journalArticle

35 Scopus citations

Abstract

N-Acyl imines, produced by the flash vacuum thermolysis of hydroxamic acid derivatives, participate in the intramolecular ene reaction to give nitrogen heterocycles. The reaction is accelerated by carboxyl substitutents on the carbon atom of the N-acyl imine, and the reaction is more successful for the production of pyrrolidine rather than piperdine derivatives.

Original languageEnglish (US)
Pages (from-to)167-174
Number of pages8
JournalJournal of Organic Chemistry
Volume51
Issue number2
DOIs
StatePublished - Jan 1 1986

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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