An Investigation of the Intramolecular Ene Reaction of N-Acyl Imines

Jyh ming Lin, Kevin Koch, Frank W. Fowler

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

N-Acyl imines, produced by the flash vacuum thermolysis of hydroxamic acid derivatives, participate in the intramolecular ene reaction to give nitrogen heterocycles. The reaction is accelerated by carboxyl substitutents on the carbon atom of the N-acyl imine, and the reaction is more successful for the production of pyrrolidine rather than piperdine derivatives.

Original languageEnglish (US)
Pages (from-to)167-174
Number of pages8
JournalJournal of Organic Chemistry
Volume51
Issue number2
DOIs
StatePublished - Jan 1 1986

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Imines
Hydroxamic Acids
Derivatives
Thermolysis
Nitrogen
Carbon
Vacuum
Atoms
pyrrolidine

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

Cite this

Lin, Jyh ming ; Koch, Kevin ; Fowler, Frank W. / An Investigation of the Intramolecular Ene Reaction of N-Acyl Imines. In: Journal of Organic Chemistry. 1986 ; Vol. 51, No. 2. pp. 167-174.
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An Investigation of the Intramolecular Ene Reaction of N-Acyl Imines. / Lin, Jyh ming; Koch, Kevin; Fowler, Frank W.

In: Journal of Organic Chemistry, Vol. 51, No. 2, 01.01.1986, p. 167-174.

Research output: Contribution to journalArticle

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