An overview of acne and its treatment.

Research output: Contribution to journalReview article

27 Citations (Scopus)

Abstract

The pathophysiology of acne vulgaris results from the interplay of follicular hyperkeratinization, the presence of Propionibacterium acnes bacteria in the follicular canal, and sebum production. Several anti-acne agents are currently available that affect one or more of these pathogenic factors and are effective against one or more acne lesion types. The only currently available agent that is directly effective against comedones is tretinoin. Agents effective against inflammatory lesions include tretinoin, benzoyl peroxide, and topical and systemic antibiotics. Agents effective against nodules and cysts include oral antibiotics and isotretinoin. However, the successful utilization of the available agents and techniques is highly dependent on an accurate and thorough assessment of each patient's needs and concerns, followed by the implementation of an individualized treatment program that has been clearly communicated to the patient. Such a program may employ several different anti-acne agents and adjunctive treatments such as comedo extraction or intralesional injection.

Original languageEnglish (US)
Pages (from-to)8-12
Number of pages5
JournalCutis; cutaneous medicine for the practitioner
Volume57
Issue number1 Suppl
StatePublished - Jan 1 1996

Fingerprint

Acne Vulgaris
Tretinoin
Benzoyl Peroxide
Intralesional Injections
Sebum
Anti-Bacterial Agents
Propionibacterium acnes
Isotretinoin
Therapeutics
Cysts
Bacteria

All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

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title = "An overview of acne and its treatment.",
abstract = "The pathophysiology of acne vulgaris results from the interplay of follicular hyperkeratinization, the presence of Propionibacterium acnes bacteria in the follicular canal, and sebum production. Several anti-acne agents are currently available that affect one or more of these pathogenic factors and are effective against one or more acne lesion types. The only currently available agent that is directly effective against comedones is tretinoin. Agents effective against inflammatory lesions include tretinoin, benzoyl peroxide, and topical and systemic antibiotics. Agents effective against nodules and cysts include oral antibiotics and isotretinoin. However, the successful utilization of the available agents and techniques is highly dependent on an accurate and thorough assessment of each patient's needs and concerns, followed by the implementation of an individualized treatment program that has been clearly communicated to the patient. Such a program may employ several different anti-acne agents and adjunctive treatments such as comedo extraction or intralesional injection.",
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An overview of acne and its treatment. / Thiboutot, D. M.

In: Cutis; cutaneous medicine for the practitioner, Vol. 57, No. 1 Suppl, 01.01.1996, p. 8-12.

Research output: Contribution to journalReview article

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AB - The pathophysiology of acne vulgaris results from the interplay of follicular hyperkeratinization, the presence of Propionibacterium acnes bacteria in the follicular canal, and sebum production. Several anti-acne agents are currently available that affect one or more of these pathogenic factors and are effective against one or more acne lesion types. The only currently available agent that is directly effective against comedones is tretinoin. Agents effective against inflammatory lesions include tretinoin, benzoyl peroxide, and topical and systemic antibiotics. Agents effective against nodules and cysts include oral antibiotics and isotretinoin. However, the successful utilization of the available agents and techniques is highly dependent on an accurate and thorough assessment of each patient's needs and concerns, followed by the implementation of an individualized treatment program that has been clearly communicated to the patient. Such a program may employ several different anti-acne agents and adjunctive treatments such as comedo extraction or intralesional injection.

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