@article{7aeb89b40b0f4fd78adf5b437abcfb18,
title = "An Ultrasensitive Calcium Reporter System via CRISPR-Cas9-Mediated Genome Editing in Human Pluripotent Stem Cells",
abstract = "Cell",
author = "Yuqian Jiang and Yuxiao Zhou and Xiaoping Bao and Chuanxin Chen and Randolph, {Lauren N.} and Jing Du and Lian, {Xiaojun Lance}",
note = "Funding Information: The project was supported by Penn State College of Engineering Multidisciplinary Research Seed Grant to X.L., Penn State Biomedical Engineering and Biology Department 's Startup funding to X.L., NIH NIBIB R21EB026035 to X.L., and Mechanical and Nuclear Engineering Department 's startup funding to J.D. The authors are also grateful to Professor Jingjing Li of Penn State University for technical assistance. Funding Information: The project was supported by Penn State College of Engineering Multidisciplinary Research Seed Grant to X.L. Penn State Biomedical Engineering and Biology Department's Startup funding to X.L. NIH NIBIB R21EB026035 to X.L. and Mechanical and Nuclear Engineering Department's startup funding to J.D. The authors are also grateful to Professor Jingjing Li of Penn State University for technical assistance. Y.J. and X.L.L. designed the experiments. Y.J. X.B. C.C. and L.N.R. performed the experiments. Y.Z. and J.D. performed the analysis of mechanical contraction. Y.J. C.C. Y.Z. X.B. L.N.R. and X.L.L. wrote the manuscript. X.L.L. approved the final draft of the manuscript. The authors declare no competing interests. Human embryonic stem cell work was approved by the Embryonic Stem Cell Oversight Committee at The Pennsylvania State University. Publisher Copyright: {\textcopyright} 2018 The Author(s)",
year = "2018",
month = nov,
day = "30",
doi = "10.1016/j.isci.2018.10.007",
language = "English (US)",
volume = "9",
pages = "27--35",
journal = "iScience",
issn = "2589-0042",
publisher = "Elsevier Inc.",
}