Abstract
Ultrasensitive magnetoelectric (ME) sensors have been developed using magnetostrictive/piezoelectric laminate heterostructures. This paper discusses a highly interdisciplinary design of a room temperature biomagnetic liver susceptometry system (BLS) based on the ME sensors. The ME-sensor based BLS maintains the ultrahigh sensitivity to detect the weak AC biomagnetic signals and introduces a low equivalent magnetic noise. The results reveal a 'turning point' and successfully indicate the output signals to be linearly responsive to iron concentrations from normal iron level (0.05 mgFe/gliver phantom) to 5 mgFe/gliver phantom iron overload level (100X overdose). Further, the introduction of the water-bag technique shows the promise on the automatic deduction of the background (tissue) signal, enabling an even higher sensitivity and better signal-to-noise (SNR). With these improvements, it becomes feasible to get improved characterization flexibility and the field distribution mapping potential via signal processing from the correlations of multiple sensors in the system. Considering the wide presence of biomagnetic signals in human organs, the potential impact of such biomagnetic devices on medicine and health care could be enormous and far-reaching.
| Original language | English (US) |
|---|---|
| Title of host publication | IEEE Sensors, SENSORS 2016 - Proceedings |
| Publisher | Institute of Electrical and Electronics Engineers Inc. |
| ISBN (Electronic) | 9781479982875 |
| DOIs | |
| State | Published - Jan 5 2017 |
| Event | 15th IEEE Sensors Conference, SENSORS 2016 - Orlando, United States Duration: Oct 30 2016 → Nov 2 2016 |
Publication series
| Name | Proceedings of IEEE Sensors |
|---|---|
| ISSN (Print) | 1930-0395 |
| ISSN (Electronic) | 2168-9229 |
Other
| Other | 15th IEEE Sensors Conference, SENSORS 2016 |
|---|---|
| Country | United States |
| City | Orlando |
| Period | 10/30/16 → 11/2/16 |
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All Science Journal Classification (ASJC) codes
- Electrical and Electronic Engineering
Cite this
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An ultrasensitive magnetoelectric sensor system for the quantitative detection of liver iron. / Xi, Hao; Lu, Meng Chien; Qian, Xiaoshi; Zhang, Qiming; Rupprecht, Sebastian; Yang, Qing.
IEEE Sensors, SENSORS 2016 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2017. 7808778 (Proceedings of IEEE Sensors).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
TY - GEN
T1 - An ultrasensitive magnetoelectric sensor system for the quantitative detection of liver iron
AU - Xi, Hao
AU - Lu, Meng Chien
AU - Qian, Xiaoshi
AU - Zhang, Qiming
AU - Rupprecht, Sebastian
AU - Yang, Qing
PY - 2017/1/5
Y1 - 2017/1/5
N2 - Ultrasensitive magnetoelectric (ME) sensors have been developed using magnetostrictive/piezoelectric laminate heterostructures. This paper discusses a highly interdisciplinary design of a room temperature biomagnetic liver susceptometry system (BLS) based on the ME sensors. The ME-sensor based BLS maintains the ultrahigh sensitivity to detect the weak AC biomagnetic signals and introduces a low equivalent magnetic noise. The results reveal a 'turning point' and successfully indicate the output signals to be linearly responsive to iron concentrations from normal iron level (0.05 mgFe/gliver phantom) to 5 mgFe/gliver phantom iron overload level (100X overdose). Further, the introduction of the water-bag technique shows the promise on the automatic deduction of the background (tissue) signal, enabling an even higher sensitivity and better signal-to-noise (SNR). With these improvements, it becomes feasible to get improved characterization flexibility and the field distribution mapping potential via signal processing from the correlations of multiple sensors in the system. Considering the wide presence of biomagnetic signals in human organs, the potential impact of such biomagnetic devices on medicine and health care could be enormous and far-reaching.
AB - Ultrasensitive magnetoelectric (ME) sensors have been developed using magnetostrictive/piezoelectric laminate heterostructures. This paper discusses a highly interdisciplinary design of a room temperature biomagnetic liver susceptometry system (BLS) based on the ME sensors. The ME-sensor based BLS maintains the ultrahigh sensitivity to detect the weak AC biomagnetic signals and introduces a low equivalent magnetic noise. The results reveal a 'turning point' and successfully indicate the output signals to be linearly responsive to iron concentrations from normal iron level (0.05 mgFe/gliver phantom) to 5 mgFe/gliver phantom iron overload level (100X overdose). Further, the introduction of the water-bag technique shows the promise on the automatic deduction of the background (tissue) signal, enabling an even higher sensitivity and better signal-to-noise (SNR). With these improvements, it becomes feasible to get improved characterization flexibility and the field distribution mapping potential via signal processing from the correlations of multiple sensors in the system. Considering the wide presence of biomagnetic signals in human organs, the potential impact of such biomagnetic devices on medicine and health care could be enormous and far-reaching.
UR - http://www.scopus.com/inward/record.url?scp=85011002738&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85011002738&partnerID=8YFLogxK
U2 - 10.1109/ICSENS.2016.7808778
DO - 10.1109/ICSENS.2016.7808778
M3 - Conference contribution
C2 - 29805722
AN - SCOPUS:85011002738
T3 - Proceedings of IEEE Sensors
BT - IEEE Sensors, SENSORS 2016 - Proceedings
PB - Institute of Electrical and Electronics Engineers Inc.
ER -