Analysis of next-generation sequencing data using galaxy

Daniel Blankenberg, Jennifer Lynne Jackson

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

The extraordinary throughput of next-generation sequencing (NGS) technology is outpacing our ability to analyze and interpret the data. This chapter will focus on practical informatics methods, strategies, and software tools for transforming NGS data into usable information through the use of a web-based platform, Galaxy. The Galaxy interface is explored through several different types of example analyses. Instructions for running one’s own Galaxy server on local hardware or on cloud computing resources are provided. Installing new tools into a personal Galaxy instance is also demonstrated.

Original languageEnglish (US)
Pages (from-to)21-43
Number of pages23
JournalMethods in Molecular Biology
Volume1150
DOIs
StatePublished - 2014

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Galaxies
Informatics
Software
Technology

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Genetics
  • Medicine(all)

Cite this

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Analysis of next-generation sequencing data using galaxy. / Blankenberg, Daniel; Jackson, Jennifer Lynne.

In: Methods in Molecular Biology, Vol. 1150, 2014, p. 21-43.

Research output: Contribution to journalArticle

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