Analytical and preparative separation of geometrical isomers by high efficiency silver nitrate liquid chromatography1

R. R. Heath, J. H. Tumlinson, R. E. Doolittle, J. H. Duncan

Research output: Contribution to journalArticlepeer-review

63 Scopus citations

Abstract

A packing technique in which carbon tetrachloride is the dispersing agent was used to pack high performance liquid chromatographic columns with 5 μm silica gel. The efficiencies obtained with analytical and preparative silica columns and AgNO3-coated silica columns packed by this technique were compared. Special considerations were taken to minimize losses in column efficiency due to the chromatographic system. The AgNO3-coated silica columns enabled the rapid separation of geometrical isomers of pheromones both analytically and preparatively. The highly efficient AgNO3silica columns gave baseline separations of some isomers on a column 5 cm in length and resulted in the development of a column in which the percentage of impregnated silver ion was critical to the separation.

Original languageEnglish (US)
Pages (from-to)10-13
Number of pages4
JournalJournal of Chromatographic Science
Volume15
Issue number1
DOIs
StatePublished - Jan 1977

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry

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