Analytical methods for separating and isolating magnetic nanoparticles

Jason R. Stephens, Jacob S. Beveridge, Mary Elizabeth Williams

Research output: Contribution to journalReview article

17 Citations (Scopus)

Abstract

Despite the large body of literature describing the synthesis of magnetic nanoparticles, few analytical tools are commonly used for their purification and analysis. Due to their unique physical and chemical properties, magnetic nanoparticles are appealing candidates for biomedical applications and analytical separations. Yet in the absence of methods for assessing and assuring their purity, the ultimate use of magnetic particles and heterostructures is likely to be limited. In this review, we summarize the separation techniques that have been initially used for this purpose. For magnetic nanoparticles, it is the use of an applied magnetic flux or field gradient that enables separations. Flow based techniques are combined with applied magnetic fields to give methods such as magnetic field flow fractionation and high gradient magnetic separation. Additional techniques have been explored for manipulating particles in microfluidic channels and in mesoporous membranes. Further development of these and new analytical tools for separation and analysis of colloidal particles is critically important to enable the practical use of these, particularly for medicinal purposes.

Original languageEnglish (US)
Pages (from-to)3280-3289
Number of pages10
JournalPhysical Chemistry Chemical Physics
Volume14
Issue number10
DOIs
StatePublished - Mar 14 2012

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Nanoparticles
nanoparticles
Magnetic fields
Magnetic separation
magnetic fields
Magnetic flux
Fractionation
gradients
Microfluidics
Chemical properties
Purification
Heterojunctions
purification
Physical properties
fractionation
chemical properties
magnetic flux
Membranes
purity
physical properties

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)
  • Physical and Theoretical Chemistry

Cite this

Stephens, Jason R. ; Beveridge, Jacob S. ; Williams, Mary Elizabeth. / Analytical methods for separating and isolating magnetic nanoparticles. In: Physical Chemistry Chemical Physics. 2012 ; Vol. 14, No. 10. pp. 3280-3289.
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Analytical methods for separating and isolating magnetic nanoparticles. / Stephens, Jason R.; Beveridge, Jacob S.; Williams, Mary Elizabeth.

In: Physical Chemistry Chemical Physics, Vol. 14, No. 10, 14.03.2012, p. 3280-3289.

Research output: Contribution to journalReview article

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