Angiotensin II receptor blockers in the prevention of complications from atrial fibrillation

Gerald V. Naccarelli, Frank Peacock

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Atrial fibrillation (AF) is the most common form of cardiac arrhythmia and is associated with an increased risk of cardiovascular morbidity and mortality, especially due to ischemic stroke. The occurrence of AF leads to atrial electrical and structural remodeling. The renin-angiotensin system appears to play a role in the development of atrial arrhythmias by its involvement in both of these processes. Large-scale hypertension trials and heart failure trials have indicated the potential value of angiotensin II receptor blockers in the treatment of AF.

Original languageEnglish (US)
Pages (from-to)783-791
Number of pages9
JournalVascular Health and Risk Management
Volume5
StatePublished - Dec 1 2009

Fingerprint

Angiotensin Receptor Antagonists
Atrial Fibrillation
Cardiac Arrhythmias
Atrial Remodeling
Renin-Angiotensin System
Heart Failure
Stroke
Hypertension
Morbidity
Mortality

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Hematology
  • Public Health, Environmental and Occupational Health
  • Cardiology and Cardiovascular Medicine
  • Pharmacology (medical)

Cite this

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Angiotensin II receptor blockers in the prevention of complications from atrial fibrillation. / Naccarelli, Gerald V.; Peacock, Frank.

In: Vascular Health and Risk Management, Vol. 5, 01.12.2009, p. 783-791.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Angiotensin II receptor blockers in the prevention of complications from atrial fibrillation

AU - Naccarelli, Gerald V.

AU - Peacock, Frank

PY - 2009/12/1

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N2 - Atrial fibrillation (AF) is the most common form of cardiac arrhythmia and is associated with an increased risk of cardiovascular morbidity and mortality, especially due to ischemic stroke. The occurrence of AF leads to atrial electrical and structural remodeling. The renin-angiotensin system appears to play a role in the development of atrial arrhythmias by its involvement in both of these processes. Large-scale hypertension trials and heart failure trials have indicated the potential value of angiotensin II receptor blockers in the treatment of AF.

AB - Atrial fibrillation (AF) is the most common form of cardiac arrhythmia and is associated with an increased risk of cardiovascular morbidity and mortality, especially due to ischemic stroke. The occurrence of AF leads to atrial electrical and structural remodeling. The renin-angiotensin system appears to play a role in the development of atrial arrhythmias by its involvement in both of these processes. Large-scale hypertension trials and heart failure trials have indicated the potential value of angiotensin II receptor blockers in the treatment of AF.

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