Anion exchange in human erythrocytes has a large activation volume

Victor A. Canfield, Robert I. Macey

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

Sulfate equilibrium exchange in human red cells has an activation volume of +150±20 cm3/mol over the pressure range 0.1 to 83 MPa (15 to 12000 lb/in2) at 30°C. This value greatly exceeds the expected contribution from sulfate binding to the anion exchanger. We suggest that the activation volume reflects conformational changes during the transport cycle.

Original languageEnglish (US)
Pages (from-to)379-384
Number of pages6
JournalBBA - Biomembranes
Volume778
Issue number2
DOIs
StatePublished - Dec 5 1984

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry
  • Cell Biology

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