ANOSPEX: A Stochastic, Spatially Explicit Model for Studying Anopheles Metapopulation Dynamics

Olugbenga O. Oluwagbemi, Christen M. Fornadel, Ezekiel F. Adebiyi, Douglas E. Norris, Jason L. Rasgon

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Anopheles mosquitoes transmit malaria, a major public health problem among many African countries. One of the most effective methods to control malaria is by controlling the Anopheles mosquito vectors that transmit the parasites. Mathematical models have both predictive and explorative utility to investigate the pros and cons of different malaria control strategies. We have developed a C++ based, stochastic spatially explicit model (ANOSPEX; Anopheles Spatially-Explicit) to simulate Anopheles metapopulation dynamics. The model is biologically rich, parameterized by field data, and driven by field-collected weather data from Macha, Zambia. To preliminarily validate ANOSPEX, simulation results were compared to field mosquito collection data from Macha; simulated and observed dynamics were similar. The ANOSPEX model will be useful in a predictive and exploratory manner to develop, evaluate and implement traditional and novel strategies to control malaria, and for understanding the environmental forces driving Anopheles population dynamics.

Original languageEnglish (US)
Article numbere68040
JournalPloS one
Volume8
Issue number7
DOIs
StatePublished - Jul 8 2013

Fingerprint

Malaria control
Anopheles
malaria
Malaria
Culicidae
Population dynamics
Public health
Medical problems
Zambia
Mathematical models
Weather
Population Dynamics
meteorological data
public health
Parasites
Theoretical Models
mathematical models
population dynamics
Public Health
parasites

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)
  • General

Cite this

Oluwagbemi, Olugbenga O. ; Fornadel, Christen M. ; Adebiyi, Ezekiel F. ; Norris, Douglas E. ; Rasgon, Jason L. / ANOSPEX : A Stochastic, Spatially Explicit Model for Studying Anopheles Metapopulation Dynamics. In: PloS one. 2013 ; Vol. 8, No. 7.
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ANOSPEX : A Stochastic, Spatially Explicit Model for Studying Anopheles Metapopulation Dynamics. / Oluwagbemi, Olugbenga O.; Fornadel, Christen M.; Adebiyi, Ezekiel F.; Norris, Douglas E.; Rasgon, Jason L.

In: PloS one, Vol. 8, No. 7, e68040, 08.07.2013.

Research output: Contribution to journalArticle

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