Anti-protein kinase NII antibodies in rheumatic autoimmune diseases

D. A. Stetler, K. M. Rose, M. E. Wenger, Cheston Berlin, S. T. Jacob

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Antibodies against nuclear protein kinase NII were detected by radioimmunoassay in the sera of patients with systemic lupus erythematosus and mixed connective tissue disease but not in sera from normal individuals or from patients with rheumatoid arthritis. Immunoglobulins derived from sera containing the antikinase antibodies inhibited the activity of protein kinase NII in vitro but had no effect on the activity of cytoplasmic cyclic AMP-dependent protein kinase.

Original languageEnglish (US)
Pages (from-to)2077-2079
Number of pages3
JournalJournal of Biological Chemistry
Volume259
Issue number4
StatePublished - Apr 5 1984

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Rheumatic Diseases
Autoimmune Diseases
Antibodies
Nuclear Proteins
Cyclic AMP-Dependent Protein Kinases
Serum
Mixed Connective Tissue Disease
Immunoglobulins
Tissue
Systemic Lupus Erythematosus
Radioimmunoassay
Rheumatoid Arthritis
protein kinase NII

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology
  • Cell Biology

Cite this

Stetler, D. A., Rose, K. M., Wenger, M. E., Berlin, C., & Jacob, S. T. (1984). Anti-protein kinase NII antibodies in rheumatic autoimmune diseases. Journal of Biological Chemistry, 259(4), 2077-2079.
Stetler, D. A. ; Rose, K. M. ; Wenger, M. E. ; Berlin, Cheston ; Jacob, S. T. / Anti-protein kinase NII antibodies in rheumatic autoimmune diseases. In: Journal of Biological Chemistry. 1984 ; Vol. 259, No. 4. pp. 2077-2079.
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Stetler, DA, Rose, KM, Wenger, ME, Berlin, C & Jacob, ST 1984, 'Anti-protein kinase NII antibodies in rheumatic autoimmune diseases', Journal of Biological Chemistry, vol. 259, no. 4, pp. 2077-2079.

Anti-protein kinase NII antibodies in rheumatic autoimmune diseases. / Stetler, D. A.; Rose, K. M.; Wenger, M. E.; Berlin, Cheston; Jacob, S. T.

In: Journal of Biological Chemistry, Vol. 259, No. 4, 05.04.1984, p. 2077-2079.

Research output: Contribution to journalArticle

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Stetler DA, Rose KM, Wenger ME, Berlin C, Jacob ST. Anti-protein kinase NII antibodies in rheumatic autoimmune diseases. Journal of Biological Chemistry. 1984 Apr 5;259(4):2077-2079.