Anti-protein kinase NII antibodies in rheumatic autoimmune diseases

D. A. Stetler, K. M. Rose, M. E. Wenger, C. M. Berlin, S. T. Jacob

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Antibodies against nuclear protein kinase NII were detected by radioimmunoassay in the sera of patients with systemic lupus erythematosus and mixed connective tissue disease but not in sera from normal individuals or from patients with rheumatoid arthritis. Immunoglobulins derived from sera containing the antikinase antibodies inhibited the activity of protein kinase NII in vitro but had no effect on the activity of cytoplasmic cyclic AMP-dependent protein kinase.

Original languageEnglish (US)
Pages (from-to)2077-2079
Number of pages3
JournalJournal of Biological Chemistry
Volume259
Issue number4
StatePublished - Apr 5 1984

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology
  • Cell Biology

Fingerprint Dive into the research topics of 'Anti-protein kinase NII antibodies in rheumatic autoimmune diseases'. Together they form a unique fingerprint.

  • Cite this

    Stetler, D. A., Rose, K. M., Wenger, M. E., Berlin, C. M., & Jacob, S. T. (1984). Anti-protein kinase NII antibodies in rheumatic autoimmune diseases. Journal of Biological Chemistry, 259(4), 2077-2079.