Anti-protein kinase NII antibodies in rheumatic autoimmune diseases

D. A. Stetler; K. M. Rose; M. E. Wenger; C. M. Berlin; S. T. Jacob

Anti-protein kinase NII antibodies in rheumatic autoimmune diseases

D. A. Stetler, K. M. Rose, M. E. Wenger, C. M. Berlin, S. T. Jacob

Research output: Contribution to journal › Article › peer-review

Abstract

Antibodies against nuclear protein kinase NII were detected by radioimmunoassay in the sera of patients with systemic lupus erythematosus and mixed connective tissue disease but not in sera from normal individuals or from patients with rheumatoid arthritis. Immunoglobulins derived from sera containing the antikinase antibodies inhibited the activity of protein kinase NII in vitro but had no effect on the activity of cytoplasmic cyclic AMP-dependent protein kinase.

Original language	English (US)
Pages (from-to)	2077-2079
Number of pages	3
Journal	Journal of Biological Chemistry
Volume	259
Issue number	4
State	Published - 1984

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Biology
Cell Biology

Fingerprint Dive into the research topics of 'Anti-protein kinase NII antibodies in rheumatic autoimmune diseases'. Together they form a unique fingerprint.

Cite this

@article{b8164a4b096f4c588a78e075700a0cc7,

title = "Anti-protein kinase NII antibodies in rheumatic autoimmune diseases",

abstract = "Antibodies against nuclear protein kinase NII were detected by radioimmunoassay in the sera of patients with systemic lupus erythematosus and mixed connective tissue disease but not in sera from normal individuals or from patients with rheumatoid arthritis. Immunoglobulins derived from sera containing the antikinase antibodies inhibited the activity of protein kinase NII in vitro but had no effect on the activity of cytoplasmic cyclic AMP-dependent protein kinase.",

author = "Stetler, {D. A.} and Rose, {K. M.} and Wenger, {M. E.} and Berlin, {C. M.} and Jacob, {S. T.}",

year = "1984",

language = "English (US)",

volume = "259",

pages = "2077--2079",

journal = "Journal of Biological Chemistry",

issn = "0021-9258",

publisher = "American Society for Biochemistry and Molecular Biology Inc.",

number = "4",

}

TY - JOUR

T1 - Anti-protein kinase NII antibodies in rheumatic autoimmune diseases

AU - Stetler, D. A.

AU - Rose, K. M.

AU - Wenger, M. E.

AU - Berlin, C. M.

AU - Jacob, S. T.

PY - 1984

Y1 - 1984

N2 - Antibodies against nuclear protein kinase NII were detected by radioimmunoassay in the sera of patients with systemic lupus erythematosus and mixed connective tissue disease but not in sera from normal individuals or from patients with rheumatoid arthritis. Immunoglobulins derived from sera containing the antikinase antibodies inhibited the activity of protein kinase NII in vitro but had no effect on the activity of cytoplasmic cyclic AMP-dependent protein kinase.

AB - Antibodies against nuclear protein kinase NII were detected by radioimmunoassay in the sera of patients with systemic lupus erythematosus and mixed connective tissue disease but not in sera from normal individuals or from patients with rheumatoid arthritis. Immunoglobulins derived from sera containing the antikinase antibodies inhibited the activity of protein kinase NII in vitro but had no effect on the activity of cytoplasmic cyclic AMP-dependent protein kinase.

UR - http://www.scopus.com/inward/record.url?scp=0021358914&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021358914&partnerID=8YFLogxK

M3 - Article

C2 - 6698957

AN - SCOPUS:0021358914

VL - 259

SP - 2077

EP - 2079

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

SN - 0021-9258

IS - 4

ER -

Anti-protein kinase NII antibodies in rheumatic autoimmune diseases

Abstract

All Science Journal Classification (ASJC) codes

Other files and links

Cite this