Antiestrogens in tumor therapy

A. Manni, O. H. Pearson

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

In the last decade a major advance in the treatment of breast cancer has been achieved with the introduction of antioestrogen therapy. The rationale behind this modality of treatment is to inhibit the peripheral action of oestrogens regardless of their circulating blood levels. This theoretically represents an advantage over endocrine ablative procedures which do not completely eliminate circulating oestrogens. It is the purpose of this paper to review the clinical use of the antioestrogen tamoxifen (Nolvadex®) in the management of advanced as well as early breast cancer. A summary will also be given on the use of tamoxifen in other malignancies.

Original languageEnglish (US)
Pages (from-to)65-75
Number of pages11
JournalClinics in Oncology
Volume1
Issue number1
StatePublished - Jan 1 1982

Fingerprint

Estrogen Receptor Modulators
Tamoxifen
Estrogens
Breast Neoplasms
Neoplasms
Therapeutics

All Science Journal Classification (ASJC) codes

  • Hematology
  • Oncology

Cite this

Manni, A., & Pearson, O. H. (1982). Antiestrogens in tumor therapy. Clinics in Oncology, 1(1), 65-75.
Manni, A. ; Pearson, O. H. / Antiestrogens in tumor therapy. In: Clinics in Oncology. 1982 ; Vol. 1, No. 1. pp. 65-75.
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Manni, A & Pearson, OH 1982, 'Antiestrogens in tumor therapy', Clinics in Oncology, vol. 1, no. 1, pp. 65-75.

Antiestrogens in tumor therapy. / Manni, A.; Pearson, O. H.

In: Clinics in Oncology, Vol. 1, No. 1, 01.01.1982, p. 65-75.

Research output: Contribution to journalArticle

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Manni A, Pearson OH. Antiestrogens in tumor therapy. Clinics in Oncology. 1982 Jan 1;1(1):65-75.