Antireflux mechanisms

A. C. Hillemeier, P. Biancani

Research output: Contribution to journalArticle

Abstract

Lower pressures are present in the kitten LES (lower esophageal sphincter) than in the adult cat. The LES pressure depends on stress developed by the LES circular muscle and t/r ratio of thickness to inner radius. Although the kitten develops higher stress than the adult, its thickness/radius ratio is low. This means that although the kitten's circular muscle can contract very well, there is just not enough of it to get the job done. Furthermore, the kitten LES circular muscle is less sensitive to muscarinic excitation. If cholinergic tonus is important in maintaining, or even just modulating LES pressure, this reduced sensitivity would result in reduced intraluminal pressure.

Original languageEnglish (US)
Pages (from-to)524-525
Number of pages2
JournalAmerican Review of Respiratory Disease
Volume131
Issue number5
StatePublished - Jan 1 1985

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Lower Esophageal Sphincter
Pressure
Muscles
Cholinergic Agents
Cats

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine

Cite this

Hillemeier, A. C. ; Biancani, P. / Antireflux mechanisms. In: American Review of Respiratory Disease. 1985 ; Vol. 131, No. 5. pp. 524-525.
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Hillemeier, AC & Biancani, P 1985, 'Antireflux mechanisms', American Review of Respiratory Disease, vol. 131, no. 5, pp. 524-525.

Antireflux mechanisms. / Hillemeier, A. C.; Biancani, P.

In: American Review of Respiratory Disease, Vol. 131, No. 5, 01.01.1985, p. 524-525.

Research output: Contribution to journalArticle

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