Application of atomic force microscope to the study of bio-cells

Bernhard Tittmann, Jikai Du, Anne Ebert, Brian Piccione

Research output: Contribution to journalConference article

1 Citation (Scopus)

Abstract

Ultrasonic atomic force microscopy (U-AFM) was used to image the elastic properties of hamster kidney (BHK) cells. Force-distance curves and finite element analysis were also used in this work assist in the description of the U-AFM images. These tools helped explain the differences in contrast seen from the center to the edge of the cell. The explanation of the U-AFM image contrast will lead to more analytical tools to investigate both nonviable and viable materials. Improvement of our system for living cell (in a culture) imaging is also discussed.

Original languageEnglish (US)
Article number02
Pages (from-to)11-18
Number of pages8
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume5768
DOIs
StatePublished - Oct 7 2005

Fingerprint

Atomic Force Microscope
Atomic Force Microscopy
Atomic force microscopy
Microscopes
ultrasonics
Ultrasonics
microscopes
atomic force microscopy
Cell
cells
hamsters
Elastic Properties
Kidney
kidneys
image contrast
Cell culture
elastic properties
Cells
Imaging
Finite Element

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

Cite this

Tittmann, Bernhard ; Du, Jikai ; Ebert, Anne ; Piccione, Brian. / Application of atomic force microscope to the study of bio-cells. In: Proceedings of SPIE - The International Society for Optical Engineering. 2005 ; Vol. 5768. pp. 11-18.
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Application of atomic force microscope to the study of bio-cells. / Tittmann, Bernhard; Du, Jikai; Ebert, Anne; Piccione, Brian.

In: Proceedings of SPIE - The International Society for Optical Engineering, Vol. 5768, 02, 07.10.2005, p. 11-18.

Research output: Contribution to journalConference article

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