Arachidonic acid metabolism by the non-pregnant human uterus

Laurence Demers, Margaret C.P. Rees, A. C. Turnbull

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Arachidonic acid metabolism in the non-pregnant human uterus was studied using short term incubations of human endometrium and myometrium with [14C] arachidonic acid followed by HPLC separation of the arachi donic acid metabolites formed. Lipoxygenase as well as cyclooxygenase activity was found in both the endometrium and myometrium although the endometrium predominated in arachidonic acid product formation. The lipoxygenase products formed by these tissues included the monohydroxy acids 5 5-HETE and 12-HETE.

Original languageEnglish (US)
Pages (from-to)175-180
Number of pages6
JournalProstaglandins, Leukotrienes and Medicine
Volume14
Issue number2
DOIs
StatePublished - Jan 1 1984

Fingerprint

Endometrium
Arachidonic Acid
Metabolism
Uterus
Lipoxygenase
Myometrium
12-Hydroxy-5,8,10,14-eicosatetraenoic Acid
Acids
Leukotriene B4
Prostaglandin-Endoperoxide Synthases
Metabolites
High Pressure Liquid Chromatography
Tissue

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physiology
  • Endocrinology

Cite this

Demers, Laurence ; Rees, Margaret C.P. ; Turnbull, A. C. / Arachidonic acid metabolism by the non-pregnant human uterus. In: Prostaglandins, Leukotrienes and Medicine. 1984 ; Vol. 14, No. 2. pp. 175-180.
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Arachidonic acid metabolism by the non-pregnant human uterus. / Demers, Laurence; Rees, Margaret C.P.; Turnbull, A. C.

In: Prostaglandins, Leukotrienes and Medicine, Vol. 14, No. 2, 01.01.1984, p. 175-180.

Research output: Contribution to journalArticle

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