Arachidonic acid metabolism by the non-pregnant human uterus

Laurence M. Demers, Margaret C.P. Rees, A. C. Turnbull

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


Arachidonic acid metabolism in the non-pregnant human uterus was studied using short term incubations of human endometrium and myometrium with [14C] arachidonic acid followed by HPLC separation of the arachi donic acid metabolites formed. Lipoxygenase as well as cyclooxygenase activity was found in both the endometrium and myometrium although the endometrium predominated in arachidonic acid product formation. The lipoxygenase products formed by these tissues included the monohydroxy acids 5 5-HETE and 12-HETE.

Original languageEnglish (US)
Pages (from-to)175-180
Number of pages6
JournalProstaglandins, Leukotrienes and Medicine
Issue number2
StatePublished - May 1984

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physiology
  • Endocrinology


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