Are any differential responses to concussive injury in civilian versus athletic populations

neuroimaging study

Brian Johnson, Andrew Dodd, Andrew R. Mayer, Mark Hallett, Semyon Slobounov

Research output: Contribution to journalArticle

Abstract

Accurate identification and classification of patients suffering from mild traumatic brain injury (mTBI) is a significant challenge faced by clinicians and researchers. To examine if there are different pathophysiological responses to concussive injury in different populations, evaluated here comparing collegiate athletes versus age-matched non-athletes. Resting-state fMRI data were acquired in the acute phase of concussion from 30 collegiate athletes and from 30 injury and age matched non-athletes. Resting-state functional connectivity measures revealed group differences with reduced connectivity in the anterior cingulate cortex (p <.05) and posterior cingulate cortex (p < 0.05) hubs of the Default Mode Network in the athletes. Given the known positive effects of exercise on brain functional reserves and neural efficiency concept, we expected less pronounced effect of concussion in athletic population. In contrast, there were significant decreases in functional connectivity in athletes that could be a result of previous repetitive subconcussive impacts and history of concussion.

Original languageEnglish (US)
JournalBrain Imaging and Behavior
DOIs
StateAccepted/In press - Jan 1 2018

Fingerprint

Neuroimaging
Athletes
Sports
Gyrus Cinguli
Wounds and Injuries
Population
Cognitive Reserve
Brain Concussion
Research Personnel
Magnetic Resonance Imaging
Exercise

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Neurology
  • Cognitive Neuroscience
  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Psychiatry and Mental health
  • Behavioral Neuroscience

Cite this

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abstract = "Accurate identification and classification of patients suffering from mild traumatic brain injury (mTBI) is a significant challenge faced by clinicians and researchers. To examine if there are different pathophysiological responses to concussive injury in different populations, evaluated here comparing collegiate athletes versus age-matched non-athletes. Resting-state fMRI data were acquired in the acute phase of concussion from 30 collegiate athletes and from 30 injury and age matched non-athletes. Resting-state functional connectivity measures revealed group differences with reduced connectivity in the anterior cingulate cortex (p <.05) and posterior cingulate cortex (p < 0.05) hubs of the Default Mode Network in the athletes. Given the known positive effects of exercise on brain functional reserves and neural efficiency concept, we expected less pronounced effect of concussion in athletic population. In contrast, there were significant decreases in functional connectivity in athletes that could be a result of previous repetitive subconcussive impacts and history of concussion.",
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Are any differential responses to concussive injury in civilian versus athletic populations : neuroimaging study. / Johnson, Brian; Dodd, Andrew; Mayer, Andrew R.; Hallett, Mark; Slobounov, Semyon.

In: Brain Imaging and Behavior, 01.01.2018.

Research output: Contribution to journalArticle

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