Assessing the impact of the diet on cardiometabolic outcomes: are multiple measurements post-intervention necessary?

Janie Allaire, Denis Talbot, Patrick Couture, André Tchernof, Peter J.H. Jones, Penny Margaret Kris-Etherton, Sheila Grace West, Philip W. Connelly, David J.A. Jenkins, Benoît Lamarche

Research output: Contribution to journalArticle

Abstract

The purpose of this study was to examine how using the mean of two consecutive measurements vs. one measurement post-treatment influences the sample size required to detect changes in cardiometabolic risk factors in dietary studies. For a given statistical power, using the mean of two measurements taken on consecutive days post-treatment instead of a single measurement significantly reduces the sample size required to observe changes in triglyceride, total apolipoprotein B100, and C-reactive protein concentrations in the context of a supplementation study. In the context of a controlled-feeding study, this gain is seen only in the case of change in triglyceride concentrations.

Original languageEnglish (US)
JournalEuropean Journal of Clinical Nutrition
DOIs
StateAccepted/In press - Jan 1 2018

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Sample Size
Triglycerides
Apolipoproteins C
Diet
C-Reactive Protein

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Allaire, Janie ; Talbot, Denis ; Couture, Patrick ; Tchernof, André ; Jones, Peter J.H. ; Kris-Etherton, Penny Margaret ; West, Sheila Grace ; Connelly, Philip W. ; Jenkins, David J.A. ; Lamarche, Benoît. / Assessing the impact of the diet on cardiometabolic outcomes : are multiple measurements post-intervention necessary?. In: European Journal of Clinical Nutrition. 2018.
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Assessing the impact of the diet on cardiometabolic outcomes : are multiple measurements post-intervention necessary? / Allaire, Janie; Talbot, Denis; Couture, Patrick; Tchernof, André; Jones, Peter J.H.; Kris-Etherton, Penny Margaret; West, Sheila Grace; Connelly, Philip W.; Jenkins, David J.A.; Lamarche, Benoît.

In: European Journal of Clinical Nutrition, 01.01.2018.

Research output: Contribution to journalArticle

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AU - Allaire, Janie

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AU - Jones, Peter J.H.

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