Assessment of antiarrhythmic drug efficacy in the treatment of supraventricular arrhythmias

Gerald Naccarelli, Anne H. Dougherty, Ellison Berns, Robert L. Rinkenberger

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Few guidelines exist for judging the efficacy of antiarrhythmic drugs in patients with supraventricular arrhythmias. Useful definitions concerning the frequency and duration of supraventricular arrhythmias are offered, and complete and partial efficacy criteria are outlined for noninvasive electrocardiographic and invasive electrophysiologic techniques. Several open label, double-blind, parallel and crossover study designs are suggested for efficacy studies concerning the termination and prevention of supraventricular tachycardia. These recommendations are useful for designing new drug trials needed to evaluate properly the efficacy of antiarrhythmic agents in the treatment of various supraventricular arrhythmias.

Original languageEnglish (US)
JournalThe American Journal of Cardiology
Volume58
Issue number5
DOIs
StatePublished - Aug 29 1986

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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