TY - JOUR
T1 - Association of a chromosomal abnormality with lymphocytes having both T and B markers in a patient with lymphoproliferative disease
AU - Siegal, Frederick P.
AU - Voss, Ruth
AU - Al-Mondhiry, Hamid
AU - Polliack, Aaron
AU - Hansen, John A.
AU - Siegal, Marta
AU - Good, Robert A.
PY - 1976/1/1
Y1 - 1976/1/1
N2 - The lymphocytes of a patient with leukemic lymphosarcoma were found to have an unusual surface phenotype in that they bound both sheep erythrocytes (a T cell marker) and complement coated erythrocytes (a B cell marker) but lacked other B cell surface characteristics. Marker chromosomes were present in these cells, but not in other, phenotypically normal cells from the same patient. This case may provide a clue to the chromosomal origin of some lymphocyte surface markers in man.
AB - The lymphocytes of a patient with leukemic lymphosarcoma were found to have an unusual surface phenotype in that they bound both sheep erythrocytes (a T cell marker) and complement coated erythrocytes (a B cell marker) but lacked other B cell surface characteristics. Marker chromosomes were present in these cells, but not in other, phenotypically normal cells from the same patient. This case may provide a clue to the chromosomal origin of some lymphocyte surface markers in man.
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U2 - 10.1016/0002-9343(76)90559-3
DO - 10.1016/0002-9343(76)90559-3
M3 - Article
C2 - 1082714
AN - SCOPUS:84886623368
VL - 60
SP - 157
EP - 166
JO - [No source information available]
JF - [No source information available]
SN - 0042-1215
IS - 1
ER -