TY - JOUR
T1 - Association of Patient Age and Gender with Kidney Stone Related Quality of Life
AU - Stern, Karen L.
AU - Gao, Tianming
AU - Antonelli, Jodi A.
AU - Viprakasit, Davis P.
AU - Averch, Timothy D.
AU - Chi, Thomas
AU - Chew, Ben H.
AU - Bird, Vincent G.
AU - Pais, Vernon M.
AU - Streeper, Necole M.
AU - Sur, Roger L.
AU - Nakada, Stephen Y.
AU - Penniston, Kristina L.
AU - Sivalingam, Sri
N1 - Publisher Copyright:
© 2019 American Urological Association Education and Research, Inc. Unauthorized reproduction of this article is prohibited.
Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.
PY - 2019/8/1
Y1 - 2019/8/1
N2 - Purpose:Kidney stone formers have lower health related quality of life than nonstone formers. The North American Stone Quality of Life Consortium is a multicenter, longitudinal, prospective study of health related quality of life in patients with kidney stones using the WISQOL (Wisconsin Stone Quality of Life Questionnaire) with data on 2,052 patients from a total of 11 centers. This study is a subanalysis of cross-sectional data looking at the association of age, gender and race on health related quality of life of stone formers.Materials and Methods:We performed multivariable analyses of ordinal logistic regression analyses to determine the impact of age, gender and race on health related quality of life, adjusting for other baseline covariates. The proportional odds assumption of ordinal logistic regression was checked. Total score and scores on 4 subdomains (social functioning, emotional functioning, stone related impact and vitality) were included.Results:Median total score for all patients was 80.4. On multivariable analysis older patients had a significantly higher total health related quality of life score than younger patients (per 10-year increase OR 1.25, p <0.0001). Male patients had higher scores than females (OR 1.56, p=0.0003) and nonCaucasian patients had lower health related quality of life than nonLatino Caucasian patients (OR 0.63, p=0.0045).Conclusions:Younger and female patients with kidney stones have lower health related quality of life than older and male patients, respectively. NonCaucasian patients with stones also have lower health related quality of life. The clinical impact of these findings might include future implications for patient counseling, including dietary and medical management of stone disease, and potential changes to the paradigm of the surgical management of stones.
AB - Purpose:Kidney stone formers have lower health related quality of life than nonstone formers. The North American Stone Quality of Life Consortium is a multicenter, longitudinal, prospective study of health related quality of life in patients with kidney stones using the WISQOL (Wisconsin Stone Quality of Life Questionnaire) with data on 2,052 patients from a total of 11 centers. This study is a subanalysis of cross-sectional data looking at the association of age, gender and race on health related quality of life of stone formers.Materials and Methods:We performed multivariable analyses of ordinal logistic regression analyses to determine the impact of age, gender and race on health related quality of life, adjusting for other baseline covariates. The proportional odds assumption of ordinal logistic regression was checked. Total score and scores on 4 subdomains (social functioning, emotional functioning, stone related impact and vitality) were included.Results:Median total score for all patients was 80.4. On multivariable analysis older patients had a significantly higher total health related quality of life score than younger patients (per 10-year increase OR 1.25, p <0.0001). Male patients had higher scores than females (OR 1.56, p=0.0003) and nonCaucasian patients had lower health related quality of life than nonLatino Caucasian patients (OR 0.63, p=0.0045).Conclusions:Younger and female patients with kidney stones have lower health related quality of life than older and male patients, respectively. NonCaucasian patients with stones also have lower health related quality of life. The clinical impact of these findings might include future implications for patient counseling, including dietary and medical management of stone disease, and potential changes to the paradigm of the surgical management of stones.
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U2 - 10.1097/JU.0000000000000291
DO - 10.1097/JU.0000000000000291
M3 - Article
C2 - 31026215
AN - SCOPUS:85069296525
VL - 202
SP - 309
EP - 313
JO - Investigative Urology
JF - Investigative Urology
SN - 0022-5347
IS - 2
ER -