Associations between objective sleep and ambulatory blood pressure in a community sample

Caroline Y. Doyle, John M. Ruiz, Daniel J. Taylor, Joshua W. Smyth, Melissa Flores, Jessica R. Dietch, Chul Ahn, Matthew Allison, Timothy W. Smith, Bert N. Uchino

Research output: Contribution to journalArticle

Abstract

Objective Epidemiologic data increasingly support sleep as a determinant of cardiovascular disease risk. Fewer studies have investigated the mechanisms underlying this relationship using objective sleep assessment approaches. Therefore, the aim of this study was to examine associations between daily blood pressure (BP) and both objectively assessed sleep duration and efficiency. Methods A diverse community sample of 300 men and women aged 21 to 70 years, enrolled in the North Texas Heart Study, participated in the study. Actigraphy-assessed sleep was monitored for two consecutive nights with ambulatory BP sampled randomly within 45-minute blocks on the first and second day as well as the second night. Results Overall, sleep duration results paralleled those of sleep efficiency. Individuals with lower sleep efficiency had higher daytime systolic (B = -0.35, SE = 0.11, p =.0018, R 2 = 0.26) but not diastolic BP (B = -0.043, SE = 0.068, p =.52, R 2 = 0.17) and higher nighttime BP (systolic: B = -0.37, SE = 0.10, p <.001, R 2 =.15; diastolic: B = -0.20, SE = 0.059, p <.001, R 2 =.14). Moreover, lower sleep efficiency on one night was associated with higher systolic (B = -0.51, SE = 0.11, p <.001, R 2 = 0.23) and diastolic BP (B = -0.17, SE = 0.065, p =.012, R 2 =.16) the following day. When «asleep» BP was taken into account instead of nighttime BP, the associations between sleep and BP disappeared. When both sleep duration and efficiency were assessed together, sleep efficiency was associated with daytime systolic BP, whereas sleep duration was associated with nighttime BP. Conclusions Lower sleep duration and efficiency are associated with higher daytime systolic BP and higher nighttime BP when assessed separately. When assessed together, sleep duration and efficiency diverge in their associations with BP at different times of day. These results warrant further investigation of these possible pathways to disease. ©

Original languageEnglish (US)
Pages (from-to)545-556
Number of pages12
JournalPsychosomatic medicine
Volume81
Issue number6
DOIs
StatePublished - Jul 1 2019

Fingerprint

Sleep
Blood Pressure
Actigraphy
Hypertension
Cardiovascular Diseases

All Science Journal Classification (ASJC) codes

  • Applied Psychology
  • Psychiatry and Mental health

Cite this

Doyle, C. Y., Ruiz, J. M., Taylor, D. J., Smyth, J. W., Flores, M., Dietch, J. R., ... Uchino, B. N. (2019). Associations between objective sleep and ambulatory blood pressure in a community sample. Psychosomatic medicine, 81(6), 545-556. https://doi.org/10.1097/PSY.0000000000000711
Doyle, Caroline Y. ; Ruiz, John M. ; Taylor, Daniel J. ; Smyth, Joshua W. ; Flores, Melissa ; Dietch, Jessica R. ; Ahn, Chul ; Allison, Matthew ; Smith, Timothy W. ; Uchino, Bert N. / Associations between objective sleep and ambulatory blood pressure in a community sample. In: Psychosomatic medicine. 2019 ; Vol. 81, No. 6. pp. 545-556.
@article{8a52f1e6de1449399b7688e948f73d79,
title = "Associations between objective sleep and ambulatory blood pressure in a community sample",
abstract = "Objective Epidemiologic data increasingly support sleep as a determinant of cardiovascular disease risk. Fewer studies have investigated the mechanisms underlying this relationship using objective sleep assessment approaches. Therefore, the aim of this study was to examine associations between daily blood pressure (BP) and both objectively assessed sleep duration and efficiency. Methods A diverse community sample of 300 men and women aged 21 to 70 years, enrolled in the North Texas Heart Study, participated in the study. Actigraphy-assessed sleep was monitored for two consecutive nights with ambulatory BP sampled randomly within 45-minute blocks on the first and second day as well as the second night. Results Overall, sleep duration results paralleled those of sleep efficiency. Individuals with lower sleep efficiency had higher daytime systolic (B = -0.35, SE = 0.11, p =.0018, R 2 = 0.26) but not diastolic BP (B = -0.043, SE = 0.068, p =.52, R 2 = 0.17) and higher nighttime BP (systolic: B = -0.37, SE = 0.10, p <.001, R 2 =.15; diastolic: B = -0.20, SE = 0.059, p <.001, R 2 =.14). Moreover, lower sleep efficiency on one night was associated with higher systolic (B = -0.51, SE = 0.11, p <.001, R 2 = 0.23) and diastolic BP (B = -0.17, SE = 0.065, p =.012, R 2 =.16) the following day. When «asleep» BP was taken into account instead of nighttime BP, the associations between sleep and BP disappeared. When both sleep duration and efficiency were assessed together, sleep efficiency was associated with daytime systolic BP, whereas sleep duration was associated with nighttime BP. Conclusions Lower sleep duration and efficiency are associated with higher daytime systolic BP and higher nighttime BP when assessed separately. When assessed together, sleep duration and efficiency diverge in their associations with BP at different times of day. These results warrant further investigation of these possible pathways to disease. {\circledC}",
author = "Doyle, {Caroline Y.} and Ruiz, {John M.} and Taylor, {Daniel J.} and Smyth, {Joshua W.} and Melissa Flores and Dietch, {Jessica R.} and Chul Ahn and Matthew Allison and Smith, {Timothy W.} and Uchino, {Bert N.}",
year = "2019",
month = "7",
day = "1",
doi = "10.1097/PSY.0000000000000711",
language = "English (US)",
volume = "81",
pages = "545--556",
journal = "Psychosomatic Medicine",
issn = "0033-3174",
publisher = "Lippincott Williams and Wilkins",
number = "6",

}

Doyle, CY, Ruiz, JM, Taylor, DJ, Smyth, JW, Flores, M, Dietch, JR, Ahn, C, Allison, M, Smith, TW & Uchino, BN 2019, 'Associations between objective sleep and ambulatory blood pressure in a community sample', Psychosomatic medicine, vol. 81, no. 6, pp. 545-556. https://doi.org/10.1097/PSY.0000000000000711

Associations between objective sleep and ambulatory blood pressure in a community sample. / Doyle, Caroline Y.; Ruiz, John M.; Taylor, Daniel J.; Smyth, Joshua W.; Flores, Melissa; Dietch, Jessica R.; Ahn, Chul; Allison, Matthew; Smith, Timothy W.; Uchino, Bert N.

In: Psychosomatic medicine, Vol. 81, No. 6, 01.07.2019, p. 545-556.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Associations between objective sleep and ambulatory blood pressure in a community sample

AU - Doyle, Caroline Y.

AU - Ruiz, John M.

AU - Taylor, Daniel J.

AU - Smyth, Joshua W.

AU - Flores, Melissa

AU - Dietch, Jessica R.

AU - Ahn, Chul

AU - Allison, Matthew

AU - Smith, Timothy W.

AU - Uchino, Bert N.

PY - 2019/7/1

Y1 - 2019/7/1

N2 - Objective Epidemiologic data increasingly support sleep as a determinant of cardiovascular disease risk. Fewer studies have investigated the mechanisms underlying this relationship using objective sleep assessment approaches. Therefore, the aim of this study was to examine associations between daily blood pressure (BP) and both objectively assessed sleep duration and efficiency. Methods A diverse community sample of 300 men and women aged 21 to 70 years, enrolled in the North Texas Heart Study, participated in the study. Actigraphy-assessed sleep was monitored for two consecutive nights with ambulatory BP sampled randomly within 45-minute blocks on the first and second day as well as the second night. Results Overall, sleep duration results paralleled those of sleep efficiency. Individuals with lower sleep efficiency had higher daytime systolic (B = -0.35, SE = 0.11, p =.0018, R 2 = 0.26) but not diastolic BP (B = -0.043, SE = 0.068, p =.52, R 2 = 0.17) and higher nighttime BP (systolic: B = -0.37, SE = 0.10, p <.001, R 2 =.15; diastolic: B = -0.20, SE = 0.059, p <.001, R 2 =.14). Moreover, lower sleep efficiency on one night was associated with higher systolic (B = -0.51, SE = 0.11, p <.001, R 2 = 0.23) and diastolic BP (B = -0.17, SE = 0.065, p =.012, R 2 =.16) the following day. When «asleep» BP was taken into account instead of nighttime BP, the associations between sleep and BP disappeared. When both sleep duration and efficiency were assessed together, sleep efficiency was associated with daytime systolic BP, whereas sleep duration was associated with nighttime BP. Conclusions Lower sleep duration and efficiency are associated with higher daytime systolic BP and higher nighttime BP when assessed separately. When assessed together, sleep duration and efficiency diverge in their associations with BP at different times of day. These results warrant further investigation of these possible pathways to disease. ©

AB - Objective Epidemiologic data increasingly support sleep as a determinant of cardiovascular disease risk. Fewer studies have investigated the mechanisms underlying this relationship using objective sleep assessment approaches. Therefore, the aim of this study was to examine associations between daily blood pressure (BP) and both objectively assessed sleep duration and efficiency. Methods A diverse community sample of 300 men and women aged 21 to 70 years, enrolled in the North Texas Heart Study, participated in the study. Actigraphy-assessed sleep was monitored for two consecutive nights with ambulatory BP sampled randomly within 45-minute blocks on the first and second day as well as the second night. Results Overall, sleep duration results paralleled those of sleep efficiency. Individuals with lower sleep efficiency had higher daytime systolic (B = -0.35, SE = 0.11, p =.0018, R 2 = 0.26) but not diastolic BP (B = -0.043, SE = 0.068, p =.52, R 2 = 0.17) and higher nighttime BP (systolic: B = -0.37, SE = 0.10, p <.001, R 2 =.15; diastolic: B = -0.20, SE = 0.059, p <.001, R 2 =.14). Moreover, lower sleep efficiency on one night was associated with higher systolic (B = -0.51, SE = 0.11, p <.001, R 2 = 0.23) and diastolic BP (B = -0.17, SE = 0.065, p =.012, R 2 =.16) the following day. When «asleep» BP was taken into account instead of nighttime BP, the associations between sleep and BP disappeared. When both sleep duration and efficiency were assessed together, sleep efficiency was associated with daytime systolic BP, whereas sleep duration was associated with nighttime BP. Conclusions Lower sleep duration and efficiency are associated with higher daytime systolic BP and higher nighttime BP when assessed separately. When assessed together, sleep duration and efficiency diverge in their associations with BP at different times of day. These results warrant further investigation of these possible pathways to disease. ©

UR - http://www.scopus.com/inward/record.url?scp=85068884551&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85068884551&partnerID=8YFLogxK

U2 - 10.1097/PSY.0000000000000711

DO - 10.1097/PSY.0000000000000711

M3 - Article

C2 - 31083055

AN - SCOPUS:85068884551

VL - 81

SP - 545

EP - 556

JO - Psychosomatic Medicine

JF - Psychosomatic Medicine

SN - 0033-3174

IS - 6

ER -