Atopic dermatitis

a clinical review for the primary care physician.

C. Walker, Timothy Craig

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

Atopic dermatitis is a common disease, causing significant morbidity. The histology and cellular mechanisms suggest that atopic dermatitis is an atopic disease similar to asthma and allergic rhinitis, with helper T type 2 lymphocytes being at least a component of the pathogenesis of the disease. Specific allergies, including food allergies, should be explored and treated. Treatment should be directed at increasing the patient's quality of life. Antihistamines, topical steroids, and lubricants are the keystones of therapy. In severe cases, oral steroids may be necessary but should be used sparingly. Interferon, cyclosporine, phototherapy, and immunosuppressive agents may be necessary in refractory cases. It appears that leukotriene inhibitors may have a future role in therapy. Clinical assessment and follow-up are important, as other atopic diseases such as asthma and allergic nasosinus disease may eventually develop in many of these patients.

Original languageEnglish (US)
JournalThe Journal of the American Osteopathic Association
Volume99
Issue number3 Suppl
StatePublished - Jan 1 1999

Fingerprint

Primary Care Physicians
Atopic Dermatitis
Asthma
Steroids
Lubricants
Phototherapy
Food Hypersensitivity
Leukotrienes
Histamine Antagonists
Immunosuppressive Agents
Helper-Inducer T-Lymphocytes
Interferons
Cyclosporine
Histology
Hypersensitivity
Therapeutics
Quality of Life
Morbidity

All Science Journal Classification (ASJC) codes

  • Complementary and alternative medicine

Cite this

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abstract = "Atopic dermatitis is a common disease, causing significant morbidity. The histology and cellular mechanisms suggest that atopic dermatitis is an atopic disease similar to asthma and allergic rhinitis, with helper T type 2 lymphocytes being at least a component of the pathogenesis of the disease. Specific allergies, including food allergies, should be explored and treated. Treatment should be directed at increasing the patient's quality of life. Antihistamines, topical steroids, and lubricants are the keystones of therapy. In severe cases, oral steroids may be necessary but should be used sparingly. Interferon, cyclosporine, phototherapy, and immunosuppressive agents may be necessary in refractory cases. It appears that leukotriene inhibitors may have a future role in therapy. Clinical assessment and follow-up are important, as other atopic diseases such as asthma and allergic nasosinus disease may eventually develop in many of these patients.",
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Atopic dermatitis : a clinical review for the primary care physician. / Walker, C.; Craig, Timothy.

In: The Journal of the American Osteopathic Association, Vol. 99, No. 3 Suppl, 01.01.1999.

Research output: Contribution to journalReview article

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