Author Correction: A naturally occurring antiviral ribonucleotide encoded by the human genome (Nature, (2018), 558, 7711, (610-614), 10.1038/s41586-018-0238-4)

Anthony S. Gizzi, Tyler L. Grove, Jamie J. Arnold, Joyce Jose, Rohit K. Jangra, Scott J. Garforth, Quan Du, Sean M. Cahill, Natalya G. Dulyaninova, James D. Love, Kartik Chandran, Anne R. Bresnick, Craig E. Cameron, Steven C. Almo

Research output: Contribution to journalComment/debate

Abstract

AIn this Letter, the isotopologue used to demonstrate hydrogen atom abstraction from CTP was incorrectly identified as 2′,3′,4′,5′,5-deutero-CTP, whereas the isotopologue we used was 3′,4′,5′,5-deutero-CTP. (Boldface indicates where changes were made.) In the main text, the sentence “Incubation of rVIP with SAM and CTP deuterated at the 2′, 3′, 4′, 5′ and 5 positions (deuCTP), increased the −m/z of 5ʹ-dA from 250.1 to 251.1, consistent with the transfer of one deuterium from deuCTP to 5ʹ-dA.” should have read “Incubation of rVIP with SAM and CTP deuterated at the 3′, 4′, 5′ and 5 positions (deuCTP) increased the −m/z of 5ʹ-dA from 250.1 to 251.1, consistent with the transfer of one deuterium from deuCTP to 5ʹ-dA.”. In the Extended Data Fig. 3 legend the sentence “When rVIP was incubated with SAM and CTP deuterated at the 2′, 3′, 4′, 5′ and 5 positions (deuCTP), the −m/z of 5′-dA increased from 250.1 to 251.1, consistent with the transfer of one deuterium from deuCTP to 5′-dA•.” should have read: “When rVIP was incubated with SAM and CTP deuterated at the 3′, 4′, 5′ and 5 positions (deuCTP), the −m/z of 5′-dA increased from 250.1 to 251.1, consistent with the transfer of one deuterium from deuCTP to 5′-dA•.”

Original languageEnglish (US)
Pages (from-to)E15
JournalNature
Volume583
Issue number7814
DOIs
StatePublished - Jul 2 2020

All Science Journal Classification (ASJC) codes

  • General

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    Gizzi, A. S., Grove, T. L., Arnold, J. J., Jose, J., Jangra, R. K., Garforth, S. J., Du, Q., Cahill, S. M., Dulyaninova, N. G., Love, J. D., Chandran, K., Bresnick, A. R., Cameron, C. E., & Almo, S. C. (2020). Author Correction: A naturally occurring antiviral ribonucleotide encoded by the human genome (Nature, (2018), 558, 7711, (610-614), 10.1038/s41586-018-0238-4). Nature, 583(7814), E15. https://doi.org/10.1038/s41586-020-2322-9