Autosomal STR variation in a Basque population

Vizcaya province

M. Zlojutro, Reena Roy, J. Palikij, M. H. Crawford

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

We have characterized 68 unrelated Basque individuals from Vizcaya, Spain, for 13 tetrameric short tandem repeat (STR) loci: CSF1PO, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D21S11, FGA, TH01, TPOX, and VWA. Interpopulational analyses were also performed for 21 European and North African population data sets for nine of the STRs typed in the Basque sample. Heterozygosity values for the Vizcayan Basques were found to be high, ranging from 0.662 to 0.882, and none of the STR loci significantly deviated from Hardy-Weinberg equilibrium. Based on the comparative population data set, the average GST score is 0.7%, indicating a low degree of genetic differentiation. However, neighbor-joining trees and multidimensional-scaling plots of DA genetic distances indicate that the Vizcayan Basques are an outlier relative to both neighboring Iberians and North African populations.

Original languageEnglish (US)
Pages (from-to)599-618
Number of pages20
JournalHuman Biology
Volume78
Issue number5
StatePublished - Oct 1 2006

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Microsatellite Repeats
microsatellite repeats
outlier
genetic differentiation
heterozygosity
Population
loci
Spain
genetic distance
genetic variation
province
sampling
Datasets
multidimensional scaling

All Science Journal Classification (ASJC) codes

  • Ecology, Evolution, Behavior and Systematics
  • Genetics
  • Genetics(clinical)

Cite this

Zlojutro, M., Roy, R., Palikij, J., & Crawford, M. H. (2006). Autosomal STR variation in a Basque population: Vizcaya province. Human Biology, 78(5), 599-618.
Zlojutro, M. ; Roy, Reena ; Palikij, J. ; Crawford, M. H. / Autosomal STR variation in a Basque population : Vizcaya province. In: Human Biology. 2006 ; Vol. 78, No. 5. pp. 599-618.
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Zlojutro, M, Roy, R, Palikij, J & Crawford, MH 2006, 'Autosomal STR variation in a Basque population: Vizcaya province', Human Biology, vol. 78, no. 5, pp. 599-618.

Autosomal STR variation in a Basque population : Vizcaya province. / Zlojutro, M.; Roy, Reena; Palikij, J.; Crawford, M. H.

In: Human Biology, Vol. 78, No. 5, 01.10.2006, p. 599-618.

Research output: Contribution to journalArticle

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Zlojutro M, Roy R, Palikij J, Crawford MH. Autosomal STR variation in a Basque population: Vizcaya province. Human Biology. 2006 Oct 1;78(5):599-618.