Azaxanthene based selective glucocorticoid receptor modulators: Design, synthesis, and pharmacological evaluation of (S)-4-(5-(1-((1,3,4-Thiadiazol-2- yl)amino)-2-methyl-1-oxopropan-2-yl)-5 H-chromeno[2,3-b]pyridin-2-yl)-2-fluoro- N, N-dimethylbenzamide (BMS-776532) and its methylene homologue (BMS-791826)

David S. Weinstein, Hua Gong, Arthur M. Doweyko, Mark Cunningham, Sium Habte, Jin Hong Wang, Deborah A. Holloway, Christine Burke, Ling Gao, Victor Guarino, Julie Carman, John E. Somerville, David Shuster, Luisa Salter-Cid, John H. Dodd, Steven G. Nadler, Joel C. Barrish

Research output: Contribution to journalArticlepeer-review

43 Scopus citations

Fingerprint

Dive into the research topics of 'Azaxanthene based selective glucocorticoid receptor modulators: Design, synthesis, and pharmacological evaluation of (S)-4-(5-(1-((1,3,4-Thiadiazol-2- yl)amino)-2-methyl-1-oxopropan-2-yl)-5 H-chromeno[2,3-b]pyridin-2-yl)-2-fluoro- N, N-dimethylbenzamide (BMS-776532) and its methylene homologue (BMS-791826)'. Together they form a unique fingerprint.

Medicine & Life Sciences

Chemical Compounds