TY - JOUR
T1 - Baroreceptor reflex failure
T2 - Review of the literature and the potential impact on patients with head and neck cancer
AU - Shah-Becker, Shivani
AU - Pennock, Michael
AU - Sinoway, Lawrence
AU - Goldenberg, David
AU - Goyal, Neerav
PY - 2017/10
Y1 - 2017/10
N2 - Background: Baroreceptor dysfunction and reflex failure may occur after surgery affecting the carotid artery. The implications for patients undergoing treatment for head and neck cancer are not well described. Methods: A literature search of PubMed was performed between March 2016 and May 2016. Search terms used individually and in combination included: “baroreflex failure,” “carotid sinus sensitivity,” “carotid endarterectomy,” “carotid body tumor,” and “head and neck cancer.” Bibliographies of included articles were also reviewed for additional pertinent articles. Results: There is evidence of baroreceptor failure in certain patients after interventions associated with the carotid artery, including carotid endarterectomy and carotid body tumor excision. Few studies have been performed investigating the potential effect of head and neck surgery treatment, including surgery and/or radiation, on baroreflex function. Conclusion: Head and neck cancer treatment has the potential to cause baroreflex failure, and this is likely an underrecognized and underdiagnosed condition.
AB - Background: Baroreceptor dysfunction and reflex failure may occur after surgery affecting the carotid artery. The implications for patients undergoing treatment for head and neck cancer are not well described. Methods: A literature search of PubMed was performed between March 2016 and May 2016. Search terms used individually and in combination included: “baroreflex failure,” “carotid sinus sensitivity,” “carotid endarterectomy,” “carotid body tumor,” and “head and neck cancer.” Bibliographies of included articles were also reviewed for additional pertinent articles. Results: There is evidence of baroreceptor failure in certain patients after interventions associated with the carotid artery, including carotid endarterectomy and carotid body tumor excision. Few studies have been performed investigating the potential effect of head and neck surgery treatment, including surgery and/or radiation, on baroreflex function. Conclusion: Head and neck cancer treatment has the potential to cause baroreflex failure, and this is likely an underrecognized and underdiagnosed condition.
UR - http://www.scopus.com/inward/record.url?scp=85021820189&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85021820189&partnerID=8YFLogxK
U2 - 10.1002/hed.24857
DO - 10.1002/hed.24857
M3 - Review article
C2 - 28675547
AN - SCOPUS:85021820189
VL - 39
SP - 2135
EP - 2141
JO - Head and Neck Surgery
JF - Head and Neck Surgery
SN - 1043-3074
IS - 10
ER -