Basement membrane: Carbohydrates and X-ray diffraction

P. A. Lee, K. Blasey, I. J. Goldstein, G. B. Pierce

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Epithelial basement membrane, synthesized by a parietal yolk sac carcinoma in vitro or in the ascites, is free of connective tissue cells and products. Carbohydrate components of this basement membrane were d-galactose, d-glucose, mannose, fucose, deoxyribose, ribose, glucosamine, and sialic acid. Total carbohydrate content was 9.50%. Galactosamine, and uronic acid were absent. This composition is compatible with previously reported analyses of basement membrane from non-neoplastic tissues. There was similarity in four out of five intensity maxima with high-angle x-ray diffraction when comparing basement membrane and collagen. A collagen or collagen-like structure may therefore be a basic structural element in epithelial basement membrane.

Original languageEnglish (US)
Pages (from-to)323-330
Number of pages8
JournalExperimental and Molecular Pathology
Volume10
Issue number3
DOIs
StatePublished - Jun 1969

Fingerprint

Basement Membrane
X-Ray Diffraction
Carbohydrates
X ray diffraction
Collagen
Tissue
Deoxyribose
Uronic Acids
Connective Tissue Cells
Galactosamine
Yolk Sac
Ribose
Fucose
Glucosamine
N-Acetylneuraminic Acid
Mannose
Galactose
Ascites
Diffraction
X-Rays

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Molecular Biology
  • Clinical Biochemistry

Cite this

Lee, P. A. ; Blasey, K. ; Goldstein, I. J. ; Pierce, G. B. / Basement membrane : Carbohydrates and X-ray diffraction. In: Experimental and Molecular Pathology. 1969 ; Vol. 10, No. 3. pp. 323-330.
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Basement membrane : Carbohydrates and X-ray diffraction. / Lee, P. A.; Blasey, K.; Goldstein, I. J.; Pierce, G. B.

In: Experimental and Molecular Pathology, Vol. 10, No. 3, 06.1969, p. 323-330.

Research output: Contribution to journalArticle

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AU - Lee, P. A.

AU - Blasey, K.

AU - Goldstein, I. J.

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