The myosin superfamily of molecular motors plays essential roles in a wide variety of cellular processes by virtue of their ability to generate force and motion through an ATP-driven cyclic interaction with actin filaments. We provide an overview of the structure, function, and biophysical properties that are common to most characterized myosins and also include examples of how myosins are adapted to perform specific cellular functions. Since many myosins are implicated in disease conditions, a complete understanding of their cellular roles and biophysical properties is critical for developing treatments for these diseases.
All Science Journal Classification (ASJC) codes
- Biochemistry, Genetics and Molecular Biology(all)