Basics of the cytoskeleton: Myosins

Omar A. Quintero, Judy E. Moore, Christopher Yengo

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

The myosin superfamily of molecular motors plays essential roles in a wide variety of cellular processes by virtue of their ability to generate force and motion through an ATP-driven cyclic interaction with actin filaments. We provide an overview of the structure, function, and biophysical properties that are common to most characterized myosins and also include examples of how myosins are adapted to perform specific cellular functions. Since many myosins are implicated in disease conditions, a complete understanding of their cellular roles and biophysical properties is critical for developing treatments for these diseases.

Original languageEnglish (US)
Title of host publicationCytoskeleton and Human Disease
PublisherHumana Press Inc.
Pages73-100
Number of pages28
Volume9781617797880
ISBN (Electronic)9781617797880
ISBN (Print)1617797871, 9781617797873
DOIs
Publication statusPublished - Dec 1 2012

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All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Quintero, O. A., Moore, J. E., & Yengo, C. (2012). Basics of the cytoskeleton: Myosins. In Cytoskeleton and Human Disease (Vol. 9781617797880, pp. 73-100). Humana Press Inc.. https://doi.org/10.1007/978-1-61779-788-0_4