Battle for the bulge: Directing small molecules to DNA and RNA defects

Research output: Contribution to journalReview article

3 Scopus citations

Abstract

Small molecules were tailored to specifically bind bulged DNA by complementing the geometry and nucleotide size of the bulge site. The prospect of generating small molecules that influence the secondary structure of DNA and RNA holds great promise for clinical applications.

Original languageEnglish (US)
Pages (from-to)854-855
Number of pages2
JournalChemistry and Biology
Volume9
Issue number8
DOIs
Publication statusPublished - Jan 1 2002

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All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmacology
  • Drug Discovery
  • Clinical Biochemistry

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