Abstract
Small molecules were tailored to specifically bind bulged DNA by complementing the geometry and nucleotide size of the bulge site. The prospect of generating small molecules that influence the secondary structure of DNA and RNA holds great promise for clinical applications.
Original language | English (US) |
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Pages (from-to) | 854-855 |
Number of pages | 2 |
Journal | Chemistry and Biology |
Volume | 9 |
Issue number | 8 |
DOIs | |
State | Published - Aug 2002 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Molecular Medicine
- Molecular Biology
- Pharmacology
- Drug Discovery
- Clinical Biochemistry