Behavioral and Social Effects of Heroin Self-Administration and Withdrawal

Thomas F. Babor, Roger E. Meyer, Steven M. Mirin, H. Brian McNamee, Mark Davies

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Behavioral and social reactions to intravenously administered heroin were studied during a 33-day experimental addiction cycle. Three groups of four subject volunteers were allowed to self-administer heroin for a ten-day period as part of a longer study of opiate antagonists. Data relevant to sleep patterns, energy expenditure, social interaction, and other observable behaviors were collected during hourly observations. Comparison of behavioral differences before and after drug administration indicated few significant acute reactions. Reactions to long-term heroin self-administration were most pronounced in the areas of sleep behavior and social interaction. Subjects tended to sleep less, especially during the initial period of acquisition, and to withdraw more from social contact. No changes were noted in energy expenditure during waking hours. The results were interpreted in terms of physiological tolerance, central nervous system arousal, and sleep deprivation.

Original languageEnglish (US)
Pages (from-to)363-367
Number of pages5
JournalArchives of General Psychiatry
Volume33
Issue number3
DOIs
StatePublished - Mar 1976

Fingerprint

Self Administration
Heroin
Sleep
Interpersonal Relations
Energy Metabolism
Opiate Alkaloids
Sleep Deprivation
Arousal
Volunteers
Central Nervous System
Pharmaceutical Preparations
Expenditure
Energy
Social Interaction

All Science Journal Classification (ASJC) codes

  • Arts and Humanities (miscellaneous)
  • Psychiatry and Mental health

Cite this

Babor, Thomas F. ; Meyer, Roger E. ; Mirin, Steven M. ; McNamee, H. Brian ; Davies, Mark. / Behavioral and Social Effects of Heroin Self-Administration and Withdrawal. In: Archives of General Psychiatry. 1976 ; Vol. 33, No. 3. pp. 363-367.
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Behavioral and Social Effects of Heroin Self-Administration and Withdrawal. / Babor, Thomas F.; Meyer, Roger E.; Mirin, Steven M.; McNamee, H. Brian; Davies, Mark.

In: Archives of General Psychiatry, Vol. 33, No. 3, 03.1976, p. 363-367.

Research output: Contribution to journalArticle

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