Beyond Purple Hearts: A Colorful Approach to Isolate Distinct Heart Cells from Human iPSCs

Lauren N. Randolph, Xiaojun Lance Lian

Research output: Contribution to journalShort survey

Abstract

In this issue of Cell Stem Cell, Zhang et al. (2019)describe a double-reporter iPSC line based on the expression of key cardiac transcription factors, TBX5 and NKX2.5, that delineates cardiac lineage specification in vitro and enables isolation of relatively pure chamber-specific cardiomyocytes, which are critical for drug screening, tissue engineering, and disease modeling.

Original languageEnglish (US)
Pages (from-to)675-677
Number of pages3
JournalCell Stem Cell
Volume24
Issue number5
DOIs
StatePublished - May 2 2019

All Science Journal Classification (ASJC) codes

  • Molecular Medicine
  • Genetics
  • Cell Biology

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