Bifurcation analysis of a thalamic relay neuron model

Huibing Yin, Charles L. Cox, Prashant G. Mehta, Uday V. Shanbhag

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Abstract

Thalamus is concerned with the relay of visual information from the retina to the visual cortex. Interestingly, the information transfer is strongly mediated by nonlinear dynamics of the neurons. In particular, experiments have shown that the thalamic neurons process visual input in two distinct nonlinear dynamic modes, the so-called tonic mode and the burst mode. This paper is concerned with a bifurcation analysis of the Hodgkin-Huxley type models of thalamic neurons. The analysis is used to show that the tonic mode arises as a type of global bifurcation where a homoclinic orbit interacts with a saddle node bifurcation in equilibria. Such a bifurcation is very efficient at the kind of rate coding that has been experimentally observed in the tonic mode. The burst mode is consistent with a subcritical Hopf bifurcation in slow currents. Finally, for both modes, the electrophysiological role of the so-called slow and fast currents is also discussed.

Original languageEnglish (US)
Title of host publication2009 American Control Conference, ACC 2009
Pages337-342
Number of pages6
DOIs
StatePublished - Nov 23 2009
Event2009 American Control Conference, ACC 2009 - St. Louis, MO, United States
Duration: Jun 10 2009Jun 12 2009

Publication series

NameProceedings of the American Control Conference
ISSN (Print)0743-1619

Other

Other2009 American Control Conference, ACC 2009
CountryUnited States
CitySt. Louis, MO
Period6/10/096/12/09

All Science Journal Classification (ASJC) codes

  • Electrical and Electronic Engineering

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