Big molecule ejection - SIMS vs. MALDI

B. J. Garrison, A. Delcorte, L. V. Zhigilei, T. E. Itina, K. D. Krantzman, Y. G. Yingling, C. M. McQuaw, E. J. Smiley, N. Winograd

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13 Scopus citations

Abstract

Using the results of molecular dynamics (MD) simulations, we discuss the question of whether the observed difference in mass limits in secondary ion mass spectrometry (SIMS) and matrix assisted laser desorption ionization (MALDI) are inherently related to the underlying physics of ejection or rather insufficient experimentation. The simulations show clearly that the physics of large molecule emission in SIMS and MALDI is very different. Consequently, we conclude that larger molecules can be ejected in MALDI than in SIMS.

Original languageEnglish (US)
Pages (from-to)69-71
Number of pages3
JournalApplied Surface Science
Volume203-204
DOIs
StatePublished - Jan 15 2003

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Condensed Matter Physics
  • Physics and Astronomy(all)
  • Surfaces and Interfaces
  • Surfaces, Coatings and Films

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    Garrison, B. J., Delcorte, A., Zhigilei, L. V., Itina, T. E., Krantzman, K. D., Yingling, Y. G., McQuaw, C. M., Smiley, E. J., & Winograd, N. (2003). Big molecule ejection - SIMS vs. MALDI. Applied Surface Science, 203-204, 69-71. https://doi.org/10.1016/S0169-4332(02)00661-X