Bilateral oophorectomy and depressive symptoms 12 months after hysterectomy

Jacqueline Rohl, Kristen Kjerulff, Patricia Langenberg, John Steege

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Objective: This study was performed to examine whether bilateral oophorectomy is related to depressive symptoms. Study Design: A secondary analysis of data collected from a cohort study of 1047 premenopausal women undergoing hysterectomy with or without concomitant oophorectomy for benign indications was performed. Data on depressive symptoms, based on the Profile of Mood States survey, were collected presurgically and 12 months postoperatively. Results: The effect of bilateral oophorectomy on postoperative depressive symptoms varied, depending on the presence of baseline depressive symptoms. Bilateral oophorectomy was associated with a decrease in risk of depressive symptoms in women without baseline depressive symptoms (risk ratio [RR] 0.36 [95% confidence interval (CI), 0.17, 0.78]) and did not change significantly in those with baseline depressive symptoms (RR 1.21 [95% CI, 0.73, 2.00]). Conclusions: Bilateral oophorectomy, in comparison with unilateral or no oophorectomy, is associated with less risk of postoperative depressive symptoms in women without baseline depressive symptoms undergoing hysterectomy.

Original languageEnglish (US)
Pages (from-to)22.e1-22.e5
JournalAmerican Journal of Obstetrics and Gynecology
Volume199
Issue number1
DOIs
StatePublished - Jan 1 2008

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Ovariectomy
Hysterectomy
Depression
Odds Ratio
Confidence Intervals
Cohort Studies

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynecology

Cite this

Rohl, Jacqueline ; Kjerulff, Kristen ; Langenberg, Patricia ; Steege, John. / Bilateral oophorectomy and depressive symptoms 12 months after hysterectomy. In: American Journal of Obstetrics and Gynecology. 2008 ; Vol. 199, No. 1. pp. 22.e1-22.e5.
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Bilateral oophorectomy and depressive symptoms 12 months after hysterectomy. / Rohl, Jacqueline; Kjerulff, Kristen; Langenberg, Patricia; Steege, John.

In: American Journal of Obstetrics and Gynecology, Vol. 199, No. 1, 01.01.2008, p. 22.e1-22.e5.

Research output: Contribution to journalArticle

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