Bilateral parotid gland enlargement and palpable nephromegaly in infant acute lymphoblastic leukemia: Case report and review of the literature

Aniket Saha, Smita Dandekar, Sarah Milla, Elizabeth Roman, Teena Bhatla

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

Acute lymphoblastic leukemia (ALL) in infants below 1 year of age accounts for 2.5% to 5% of childhood ALL. Most children with ALL present with fever, bruising, mucosal bleeding, bone pain, pallor, hepatosplenomegaly, and lymphadenopathy. Common sites of extramedullary involvement at diagnosis include liver, spleen, lymph nodes, brain, and testes. Nephromegaly has also been reported. We present a novel case of bilateral parotid enlargement along with bilateral palpable nephromegaly in a patient with newly diagnosed infant ALL. This unique presentation highlights the importance of considering ALL in the differential diagnosis of parotid enlargement especially when associated with abnormal blood counts.

Original languageEnglish (US)
Pages (from-to)246-248
Number of pages3
JournalJournal of Pediatric Hematology/Oncology
Volume36
Issue number3
DOIs
StatePublished - Jan 1 2014

Fingerprint

Parotid Gland
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Pallor
Testis
Differential Diagnosis
Fever
Spleen
Lymph Nodes
Hemorrhage
Bone and Bones
Pain
Liver
Brain

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Oncology
  • Hematology

Cite this

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abstract = "Acute lymphoblastic leukemia (ALL) in infants below 1 year of age accounts for 2.5{\%} to 5{\%} of childhood ALL. Most children with ALL present with fever, bruising, mucosal bleeding, bone pain, pallor, hepatosplenomegaly, and lymphadenopathy. Common sites of extramedullary involvement at diagnosis include liver, spleen, lymph nodes, brain, and testes. Nephromegaly has also been reported. We present a novel case of bilateral parotid enlargement along with bilateral palpable nephromegaly in a patient with newly diagnosed infant ALL. This unique presentation highlights the importance of considering ALL in the differential diagnosis of parotid enlargement especially when associated with abnormal blood counts.",
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Bilateral parotid gland enlargement and palpable nephromegaly in infant acute lymphoblastic leukemia : Case report and review of the literature. / Saha, Aniket; Dandekar, Smita; Milla, Sarah; Roman, Elizabeth; Bhatla, Teena.

In: Journal of Pediatric Hematology/Oncology, Vol. 36, No. 3, 01.01.2014, p. 246-248.

Research output: Contribution to journalReview article

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AU - Bhatla, Teena

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AB - Acute lymphoblastic leukemia (ALL) in infants below 1 year of age accounts for 2.5% to 5% of childhood ALL. Most children with ALL present with fever, bruising, mucosal bleeding, bone pain, pallor, hepatosplenomegaly, and lymphadenopathy. Common sites of extramedullary involvement at diagnosis include liver, spleen, lymph nodes, brain, and testes. Nephromegaly has also been reported. We present a novel case of bilateral parotid enlargement along with bilateral palpable nephromegaly in a patient with newly diagnosed infant ALL. This unique presentation highlights the importance of considering ALL in the differential diagnosis of parotid enlargement especially when associated with abnormal blood counts.

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