Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine

Justin Lee Brown, Sangamesh G. Kumbar, Brittany L. Banik

Research output: Book/ReportBook

1 Citation (Scopus)

Abstract

Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine explores musculoskeletal tissue growth and development across populations, ranging from elite athletes to the elderly. The regeneration and reparation of musculoskeletal tissues present the unique challenges of requiring both the need to withstand distinct forces applied to the body and ability to support cell populations. The book is separated into sections based on tissue type, including bone, cartilage, ligament and tendon, muscle, and musculoskeletal tissue interfaces. Within each tissue type, the chapters are subcategorized into strategies focused on cells, hydrogels, polymers, and other materials (i.e. ceramics and metals) utilized in musculoskeletal tissue engineering applications. In each chapter, the relationships that exist amongst the strategy, stem cell differentiation and somatic cell specialization at the intracellular level are emphasized. Examples include intracellular signaling through growth factor delivery, geometry sensing of the surrounding network, and cell signaling that stems from altered population dynamics. Presents a self-contained work for the field of musculoskeletal tissue engineering and regenerative medicine. Focuses on how materials of structures can be designed to be resistant while promoting viable grafts. Contains major tissue types that are covered with a strategy for each material and structure.

Original languageEnglish (US)
PublisherElsevier Inc.
Number of pages239
ISBN (Electronic)9780128033999
ISBN (Print)9780128033944
StatePublished - Nov 1 2016

Fingerprint

Scaffolds (biology)
Tissue engineering
Tissue
Cell signaling
Population dynamics
Hydrogels
Ligaments
Tendons
Cartilage
Ceramic materials
Stem cells
Grafts
Muscle
Regenerative Medicine
Intercellular Signaling Peptides and Proteins
Polymers
Bone
Metals
Cells
Geometry

All Science Journal Classification (ASJC) codes

  • Engineering(all)
  • Materials Science(all)

Cite this

Brown, Justin Lee ; Kumbar, Sangamesh G. ; Banik, Brittany L. / Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine. Elsevier Inc., 2016. 239 p.
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Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine. / Brown, Justin Lee; Kumbar, Sangamesh G.; Banik, Brittany L.

Elsevier Inc., 2016. 239 p.

Research output: Book/ReportBook

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