Bioactive Glass Innovations Through Academia-Industry Collaboration

Qiang Fu, John Mauro, Mohamed N. Rahaman

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Since the discovery of 45S5 bioactive glass by Hench in 1969, numerous studies have been conducted on the use of bioactive glasses for the repair of hard and soft tissues. However, limited progress has been achieved in the commercialization of bioactive glass as medical products, with the most successful ones being 45S5-based Perioglas®, Novabone®, and NovaMin®. This indicates that a gap exists between academic research and industrial scale-up. Our work attempts to provide a preliminary study on the two well-known bioactive glasses, 45S5 and 13-93, to evaluate their suitability for mass production in an industrial platform. Glass properties including strain, annealing, and softening points, thermal expansion, density, and liquidus temperature are characterized. Our results show that both glasses have a substantially lower liquidus viscosity than soda lime silicate (SLS) glass, suggesting that melting and forming them in an industrial continuous-unit melting system could be challenging. Innovations in bioactive glass compositions by delving into literature, referencing relevant phase diagrams, conducting design of experiments (DOE), and utilizing modeling tools are needed. Furthermore, joint research between academia and industry on the development of new forming techniques is critical to meet the increasing demand for bioactive glass in a variety of sizes and shapes.

Original languageEnglish (US)
Pages (from-to)139-146
Number of pages8
JournalInternational Journal of Applied Glass Science
Volume7
Issue number2
DOIs
StatePublished - Jan 1 2016

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Bioactive glass
Innovation
Glass
Industry
Melting
Silicates
Design of experiments
Phase diagrams
Thermal expansion
Repair
Annealing
Viscosity
Tissue
Lime
Chemical analysis
Temperature
Bioglass
bioactive glass 45S5

All Science Journal Classification (ASJC) codes

  • Materials Science(all)

Cite this

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Bioactive Glass Innovations Through Academia-Industry Collaboration. / Fu, Qiang; Mauro, John; Rahaman, Mohamed N.

In: International Journal of Applied Glass Science, Vol. 7, No. 2, 01.01.2016, p. 139-146.

Research output: Contribution to journalArticle

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