The bioconversion of biomass is a means to produce industrially important chemicals such as lactate, acetate, and ethanol. For this purpose, the feasibility of using the hyperthermophiles Thermotoga maritima and Methanococcus jannaschii was evaluated. A more complete analysis of the pyrolysis and hydrolysis mixture compositions and of the products generated upon extremophilic conversion was presented. This will lead to the development a hybrid thermochemical and extremophile bioconversion process for the production of high value products from agricultural wastes. This is an abstract of a paper presented at the AIChE Annual Meeting (San Francisco, CA 11/12-17/2006).