Biological synthesis of cationic gold nanoparticles and binding of plasmid DNA

D. Raju, Rishi K. Vishwakarma, Bashir M. Khan, Urmil J. Mehta, Absar Ahmad

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Nanobiotechnology is the development of eco-friendly experimental processes for the synthesis of nanomaterials. The present work focuses on synthesis of cationic gold nanoparticles (C-GNPs) for biological applications, especially in gene and drug delivery studies. A biosynthesis methodology has been developed for the functionalization of gold nanoparticles to cationic nature. The synthesis of C-GNPs was done by using peanut leaf extract in the presence of cysteamine. The formed C-GNPs were characterized by using UV-visible spectroscopy (UV-vis), the particles sizes and shapes were confirmed by a Transmission electron microscope (TEM) and crystallinity of C-GNPs was characterized by diffraction. The binding of plasmid DNA on the C-GNPs was confirmed by agarose gel electrophoresis.

Original languageEnglish (US)
Pages (from-to)159-161
Number of pages3
JournalMaterials Letters
Volume129
DOIs
StatePublished - Aug 15 2014

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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